Patient motion impacts single photon emission computed tomography (SPECT), positron
emission tomography (PET) and x-ray computed tomography (CT) by giving rise to …

This paper reviews recent advances in 4D medical imaging (4DMI) and 4D radiation therapy
(4DRT), which study, characterize, and minimize patient motion during the processes of …

Objective: The purpose of this study was to determine whether microglial activity, measured
using translocator-protein positron emission tomography (PET) imaging, is increased in …

Background Quantitative in vivo imaging of myelin loss and repair in patients with multiple
sclerosis (MS) is essential to understand the pathogenesis of the disease and to evaluate …

Context A major limitation on the development of biomarkers and novel interventions for
schizophrenia is that its pathogenesis is unknown. Although elevated striatal dopamine …

Importance The dopamine hypothesis suggests that dopamine abnormalities underlie
psychosis, irrespective of diagnosis, implicating dopamine dysregulation in bipolar affective …

Troublesome involuntary movements in the absence of dopaminergic medication, so-called
off-medication dyskinesias, are a serious adverse effect of fetal neural grafts that hinders the …

Thirty Parkinson's disease (PD) patients were divided into three equal groups according to
their disease duration while 10 normal healthy volunteers matched for age and sex served …

Context Alterations in dopaminergic neurotransmission and function of the prefrontal cortex
are thought to be central to the pathophysiology of schizophrenia, but the relationship …

Idiopathic Parkinson's disease (PD) is often accompanied by a pattern of executive deficits
similar to those found in patients with frontal lobe lesions. We investigated whether such …