Magnetic resonance imaging (MRI) provides excellent soft-tissue contrast for clinical
diagnoses and research which underpin many recent breakthroughs in medicine and …

MRtrix3 is an open-source, cross-platform software package for medical image processing,
analysis and visualisation, with a particular emphasis on the investigation of the brain using …

Psilocybin therapy shows antidepressant potential, but its therapeutic actions are not well
understood. We assessed the subacute impact of psilocybin on brain function in two clinical …

Psychedelics have attracted medical interest, but their effects on human brain function are
incompletely understood. In a comprehensive, within-subjects, placebo-controlled design …

Astrocytes provide key neuronal support, and their phenotypic transformation is implicated in
neurodegenerative diseases. Metabolically, astrocytes possess low mitochondrial oxidative …

Although the general location of functional neural networks is similar across individuals,
there is vast person-to-person topographic variability. To capture this, we implemented …

The mechanisms underlying phenotypic heterogeneity in autism spectrum disorder (ASD)
are not well understood. Using a large neuroimaging dataset, we identified three latent …

Individual differences in brain functional organization track a range of traits, symptoms and
behaviours,,,,,,,,,,–. So far, work modelling linear brain–phenotype relationships has …

Objective Randomized clinical trials have shown that aerobic exercise attenuates motor
symptom progression in Parkinson's disease, but the underlying neural mechanisms are …

Western diets rich in fat and sugar promote excess calorie intake and weight gain; however,
the underlying mechanisms are unclear. Despite a well-documented association between …