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Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
[HTML][HTML] Golden Syrian hamster models for cancer research
Z Wang, RT Cormier - Cells, 2022 - mdpi.com
The golden Syrian hamster (Mesocricetus auratus) has long been a valuable rodent model
of human diseases, especially infectious and metabolic diseases. Hamsters have also been …
of human diseases, especially infectious and metabolic diseases. Hamsters have also been …
Total flavonoids of Taraxacum mongolicum inhibit non-small cell lung cancer by regulating immune function
L Kang, Y Song, X Fang, J Zhang, Y Zhang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Taraxacum mongolicum Hand.-Mazz. has been
used in lung cancer treatment in Chinese medicine. However, its specific mechanism of …
used in lung cancer treatment in Chinese medicine. However, its specific mechanism of …
Esophageal organoids: applications and future prospects
H Liu, X Wang - Journal of Molecular Medicine, 2023 - Springer
Organoids have been developed in the last decade as a new research tool to simulate
organ cell biology and disease. Compared to traditional 2D cell lines and animal models …
organ cell biology and disease. Compared to traditional 2D cell lines and animal models …
Patient-derived tumor models: a suitable tool for preclinical studies on esophageal cancer
F Liang, H Xu, H Cheng, Y Zhao, J Zhang - Cancer Gene Therapy, 2023 - nature.com
Esophageal cancer (EC) is the tenth most common cancer worldwide and has high
morbidity and mortality. Its main subtypes include esophageal squamous cell carcinoma and …
morbidity and mortality. Its main subtypes include esophageal squamous cell carcinoma and …
Esophageal adenocarcinoma models: a closer look
Esophageal adenocarcinoma (EAC) is a subtype of esophageal cancer with significant
morbidity and mortality rates worldwide. Despite advancements in tumor models, the …
morbidity and mortality rates worldwide. Despite advancements in tumor models, the …
Application of patient derived xenograft model in personalized drug screening for chondrosarcoma of head and neck: A preclinical study
Y Hua, Z Guo, Y Wang, C Li, B Yan - Oral Oncology, 2025 - Elsevier
Objectives The effect of radiotherapy and chemotherapy on head and neck chondrosarcoma
(HNCS) has not been unanimously determined because of the rarity of HNCS. Patient …
(HNCS) has not been unanimously determined because of the rarity of HNCS. Patient …
circFIG 4 drives the carcinogenesis and metastasis of esophagus cancer via the miR‐493‐5p/E2F3 axis
Z Huang, C Wang, X Zhao - Thoracic Cancer, 2022 - Wiley Online Library
Background Esophageal cancer (EC) is a highly malignant tumor of the digestive tract.
Circular RNAs (circRNAs) have been verified to play a regulatory role in the occurrence and …
Circular RNAs (circRNAs) have been verified to play a regulatory role in the occurrence and …
[HTML][HTML] Patient-derived xenograft models: Current status, challenges, and innovations in cancer research
M qi Liu, X Yang - Genes & Diseases, 2025 - Elsevier
Despite advancing therapeutic treatments, cancer remains the leading cause of death
worldwide, with most of its patients develo** drug resistance and recurrence after initial …
worldwide, with most of its patients develo** drug resistance and recurrence after initial …
HDS screening with patient-derived primary cells guided individualized therapy for esophageal squamous cell carcinoma–in vivo and vitro
X He, H Yan, J Hu, X Duan, M Zhang, H Li… - Frontiers in …, 2023 - frontiersin.org
Objective To analyze and evaluate the role of the High-throughput Drug Sensitivity (HDS)
screening strategy in identifying highly sensitive drugs against esophageal squamous cell …
screening strategy in identifying highly sensitive drugs against esophageal squamous cell …