Epigenetics of glioblastoma multiforme: From molecular mechanisms to therapeutic approaches
Glioblastoma multiforme (GBM) is the most common form of brain cancer and one of the
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …
most aggressive cancers found in humans. Most of the signs and symptoms of GBM can be …
MicroRNA and cancer–a brief overview
MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer …
S Huang, X Ge, J Yu, Z Han, Z Yin, Y Li… - The FASEB …, 2018 - Wiley Online Library
Neuronal inflammation is the characteristic pathologic change of acute neurologic
impairment and chronic traumatic encephalopathy after traumatic brain injury (TBI) …
impairment and chronic traumatic encephalopathy after traumatic brain injury (TBI) …
Long Noncoding RNA NEAT1, Regulated by the EGFR Pathway, Contributes to Glioblastoma Progression Through the WNT/β-Catenin Pathway by Scaffolding EZH2
Abstract Purpose: Long noncoding RNAs have been implicated in gliomagenesis, but their
mechanisms of action are mainly undocumented. Through public glioma mRNA expression …
mechanisms of action are mainly undocumented. Through public glioma mRNA expression …
Genetics of adult glioma
MKL Goodenberger, RB Jenkins - Cancer genetics, 2012 - Elsevier
Gliomas make up approximately 30% of all brain and central nervous system tumors and
80% of all malignant brain tumors. Despite the frequency of gliomas, the etiology of these …
80% of all malignant brain tumors. Despite the frequency of gliomas, the etiology of these …
[HTML][HTML] Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy
Q Zhan, K Yi, H Qi, S Li, X Li, Q Wang, Y Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Develo** an effective nanoplatform to realize'multi-in-one'is essential to
broaden the therapeutic potential of combination therapy. Exosomes are ideal candidates …
broaden the therapeutic potential of combination therapy. Exosomes are ideal candidates …
Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis
JX Zhang, W Song, ZH Chen, JH Wei, YJ Liao… - The lancet …, 2013 - thelancet.com
Background Current staging methods do not accurately predict the risk of disease
recurrence and benefit of adjuvant chemotherapy for patients who have had surgery for …
recurrence and benefit of adjuvant chemotherapy for patients who have had surgery for …
Overview upon miR-21 in lung cancer: focus on NSCLC
Considering the high mortality rate encountered in lung cancer, there is a strong need to
explore new biomarkers for early diagnosis and also improved therapeutic targets to …
explore new biomarkers for early diagnosis and also improved therapeutic targets to …
[HTML][HTML] Exosomal miRNAs in central nervous system diseases: biomarkers, pathological mediators, protective factors and therapeutic agents
Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …
Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs
Background Cell-derived microvesicles (MVs) have been described as a new mechanism of
cell-to-cell communication. MVs after internalization within target cells may deliver genetic …
cell-to-cell communication. MVs after internalization within target cells may deliver genetic …