Stimuli-responsive nano-assemblies from amphiphilic macromolecules could undergo
controlled structural transformations and generate diverse macroscopic phenomenon under …

The solid tumors provide a series of biological barriers in cellular microenvironment for
designing drug delivery methods based on advanced stimuli-responsive materials. These …

Owing to the high effective release and uptake merits, the ordered porous nanostructure as
the drug-loaded delivery nano-systems is fascinating to the sustained release formulations …

The physiological instability of nanocarriers, premature drug leakage during blood
circulation, and associated severe side effects cause compromised therapeutic efficacy …

Targeted drug delivery using antibody–drug conjugates has attracted great attention due to
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …

In this work, doxorubicin (Dox)-encapsulated poly (vinyl caprolactam)(PVCL)-based three-
dimensional nanogel networks were developed and were crosslinked with disulfide …

Stimuli-responsive amphiphilic polymers are known to be precursors to forming promising
nanoarchitectonics with tunable properties for application in biomedical sciences. Currently …

Targeted delivery of therapeutics using antibody–nanogel conjugates (ANCs) with a high
drug-to-antibody ratio has the potential to overcome some of the inherent limitations of …

Switchable polymeric materials, which can respond to triggering signals through changes in
their properties, have become a major research focus for parenteral controlled delivery …

Doxorubicin (Dox) is known for its potential to deliver desirable anticancer effects against
various types of cancer including colorectal cancer. However, the adverse effects are …