Structural determinants of stimuli-responsiveness in amphiphilic macromolecular nano-assemblies

H Liu, HH Lu, Y Alp, R Wu, S Thayumanavan - Progress in Polymer …, 2024 - Elsevier
Stimuli-responsive nano-assemblies from amphiphilic macromolecules could undergo
controlled structural transformations and generate diverse macroscopic phenomenon under …

Intertumoral and intratumoral barriers as approaches for drug delivery and theranostics to solid tumors using stimuli-responsive materials

KK Chenab, H Malektaj, AAR Nadinlooie… - Microchimica Acta, 2024 - Springer
The solid tumors provide a series of biological barriers in cellular microenvironment for
designing drug delivery methods based on advanced stimuli-responsive materials. These …

Degradable polymer-based nanoassemblies for precise targeting and drug delivery to breast cancer cells without affecting normal healthy cells

S Santra, S Das, S Dey, A Sengupta, B Giri… - …, 2024 - ACS Publications
Stimuli-responsive amphiphilic polymers are known to be precursors to forming promising
nanoarchitectonics with tunable properties for application in biomedical sciences. Currently …

Mace-shaped NH2-Uio-66-modified HNTs as sustained release nanocarrier of loading pyraclostrobin against the grey mould

W Zhu, L Sun, H Hu, J Feng, Z Cheng - Applied Surface Science, 2024 - Elsevier
Owing to the high effective release and uptake merits, the ordered porous nanostructure as
the drug-loaded delivery nano-systems is fascinating to the sustained release formulations …

Redox-Responsive Core-Cross-Linked Micelles of Miktoarm Poly(ethylene oxide)-b-poly(furfuryl methacrylate) for Anticancer Drug Delivery

P Kumar, SH Kim, S Yadav, SH Jo, S Yoo… - … Applied Materials & …, 2023 - ACS Publications
The physiological instability of nanocarriers, premature drug leakage during blood
circulation, and associated severe side effects cause compromised therapeutic efficacy …

Poly (vinyl alcohol)-Incorporated Core–Shell Polymer Nanogels Functionalized by Block Copolymer Installation for Cisplatin Delivery

Y Kitayama, S Takigawa, E Yuba, A Harada - Biomacromolecules, 2024 - ACS Publications
The functionalization approach for nanomaterials is of great importance for their application
in drug delivery systems. Herein, an approach based on block copolymer installation into …

Targeted drug delivery using a plug-to-direct antibody–nanogel conjugate

U Huynh, P Wu, J Qiu, T Prachyathipsakul… - …, 2023 - ACS Publications
Targeted drug delivery using antibody–drug conjugates has attracted great attention due to
its enhanced therapeutic efficacy compared to traditional chemotherapy. However, the …

[HTML][HTML] Dual responsive poly (vinyl caprolactam)-based nanogels for tunable intracellular doxorubicin delivery in cancer cells

KM Rao, M Suneetha, DV Kumar, HJ Kim, YJ Seok… - Pharmaceutics, 2022 - mdpi.com
In this work, doxorubicin (Dox)-encapsulated poly (vinyl caprolactam)(PVCL)-based three-
dimensional nanogel networks were developed and were crosslinked with disulfide …

[HTML][HTML] Opportunities and challenges of switchable materials for pharmaceutical use

DC Tuncaboylu, C Wischke - Pharmaceutics, 2022 - mdpi.com
Switchable polymeric materials, which can respond to triggering signals through changes in
their properties, have become a major research focus for parenteral controlled delivery …

Multiplexed analysis of the cellular uptake of polymeric nanocarriers

DK Agrohia, P Wu, U Huynh, S Thayumanavan… - Analytical …, 2022 - ACS Publications
Polymeric nanocarriers (PNCs) are versatile drug delivery vehicles capable of delivering a
variety of therapeutics. Quantitatively monitoring their uptake in biological systems is …