Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021‏ - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Cerebral small vessel disease: a review focusing on pathophysiology, biomarkers, and machine learning strategies

E Cuadrado-Godia, P Dwivedi, S Sharma… - Journal of …, 2018‏ - pmc.ncbi.nlm.nih.gov
Cerebral small vessel disease (cSVD) has a crucial role in lacunar stroke and brain
hemorrhages and is a leading cause of cognitive decline and functional loss in elderly …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022‏ - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Cerebral small vessel disease

J Litak, M Mazurek, B Kulesza, P Szmygin… - International journal of …, 2020‏ - mdpi.com
Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders
with different pathological backgrounds. The advanced vasculature net of cerebral vessels …

The association between glymphatic system dysfunction and cognitive impairment in cerebral small vessel disease

J Tang, M Zhang, N Liu, Y Xue, X Ren… - Frontiers in aging …, 2022‏ - frontiersin.org
The mechanism of cognitive impairment in patients with cerebral small vessel disease
(CSVD) remains unknown. The glymphatic system dysfunction, which has been …

[HTML][HTML] Clinical relevance of cerebral small vessel diseases

M Pasi, C Cordonnier - Stroke, 2020‏ - journals.lww.com
Until recent years, cerebral small vessel disease (SVD) has drawn little attention mostly
because small cerebral arteries were difficult to observe in imaging and in vivo studies …

Mixed-location cerebral hemorrhage/microbleeds: underlying microangiopathy and recurrence risk

M Pasi, A Charidimou, G Boulouis, E Auriel, A Ayres… - Neurology, 2018‏ - neurology.org
Objective To assess the predominant type of cerebral small vessel disease (SVD) and
recurrence risk in patients who present with a combination of lobar and deep intracerebral …

A practical approach to the management of cerebral amyloid angiopathy

MG Kozberg, V Perosa, ME Gurol… - … Journal of Stroke, 2021‏ - journals.sagepub.com
Cerebral amyloid angiopathy is a common small vessel disease in the elderly involving
vascular amyloid-β deposition. Cerebral amyloid angiopathy is one of the leading causes of …

Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia …

A Low, MA Prats-Sedano, E McKiernan… - Alzheimer's research & …, 2022‏ - Springer
Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …

The growing clinical spectrum of cerebral amyloid angiopathy

MJH Wermer, SM Greenberg - Current opinion in neurology, 2018‏ - journals.lww.com
CAA should be in the differential diagnosis of elderly patients with lobar ICH but also in
those with cognitive decline and episodic transient neurological symptoms. Physicians …