The immune system regulates angiogenesis in cancer with both pro-and antiangiogenic
activities. The induction of angiogenesis is mediated by tumor-associated macrophages and …

Recent advances in treatment of metastatic renal cell carcinoma (RCC), such as new
molecular therapies that use novel antiangiogenic agents, have led to revision of the most …

Quantitative imaging (QI) is increasingly applied in modern radiology practice, assisting in
the clinical assessment of many patients and providing a source of biomarkers for a …

Background Despite a 5-year overall survival rate of 58 per cent after liver resection for
colorectal liver metastases (CLMs), more than half of patients develop recurrence …

Most methods define a limited number of “target” lesions to be measured and other “non-
target” lesions to be evaluated qualitatively. RECIST criteria are the most widely used …

For the past decade, advanced renal cell carcinoma (RCC) has been at the forefront of
oncologic innovation. Our rapidly evolving understanding of the molecular and genetic basis …

BACKGROUND: Vascular endothelial growth factor (VEGF)-targeted therapy has become
standard treatment for patients with metastatic renal cell cancer (mRCC). Since these …

Study Type–Prognosis (cohort series) Level of Evidence 2b What's known on the subject?
and What does the study add? In the literature, few studies have evaluated the role of …

Perfusion CT was first described in the 1970s but has become accepted as a clinical
technique in recent years. In oncological practice Perfusion CT allows the downstream …

The aims of this cohort study were to evaluate initial tumor hypoxia in metastatic renal cell
carcinoma (mRCC) and its changes after sunitinib treatment, using 18F-fluoromisonidazole …