Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces
significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU …

Abstract Coronavirus disease 2019 (COVID-19) is a rapidly emerging disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease begins as an …

Abstract The coronavirus disease 2019 (COVID-19) pandemic continues to cause morbidity
and mortality. Since SARS coronavirus 2 (SARS-CoV-2) was identified as the cause for …

Abstract Background Since December 2019, the COVID-19 pandemic has changed the
concept of medicine. This work aims to analyze the use of antibiotics in patients admitted to …

The complement component C3 is a fundamental plasma protein for host defense, produced
largely by the liver. However, recent work has demonstrated the critical importance of tissue …

Untangling the interdependency of infections, immunity and frailty may help to clarify their
roles in the maintenance of health in aging individuals, and the recent COVID-19 pandemic …

Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

Acute respiratory distress syndrome (ARDS) is characterized by massive inflammation,
increased vascular permeability and pulmonary edema. Mortality due to ARDS remains very …

Huang-Lian-Jie-Du decoction (HLJDD) has been used to treat pneumonia for thousands of
years in China. However, our understanding of its mechanisms on treating pneumonia is still …

Despite the widespread application of vaccination programs and antiviral drug treatments,
influenza viruses are still among the most harmful human pathogens. Indeed, influenza …