Necrotizing Soft-Tissue Infections | New England Journal of Medicine Skip to main content
Access provided byUT MD ANDERSON CANCER CENTER The New England Journal of …

Background Chronic wounds are common and present a health problem with significant
effect on quality of life. Various pathologies may cause tissue breakdown, including poor …

1. Foot infections in patients with diabetes cause substantial morbidity and frequent visits to
health care professionals and may lead to amputation of a lower extremity. 2. Diabetic foot …

The state of wound oxygenation is a key determinant of healing outcomes. From a
diagnostic standpoint, measurements of wound oxygenation are commonly used to guide …

Hyperbaric oxygen therapy (HBO) is increasingly used in a number of areas of medical
practice. It is a unique intervention whose method of action is not well understood. Clinicians …

Necrotizing fasciitis (NF) is a deep-seated infection, the diagnosis of which is made by
surgical inspection where the hallmarks include friability of the superficial fascia (ie, the so …

Infectious myositis may be caused by a broad range of bacterial, fungal, parasitic, and viral
agents. Infectious myositis is overall uncommon given the relative resistance of the …

BACKGROUND: Nonhealing wounds are a major, functionally-limiting medical problem
impairing quality of life for millions of people each year. Various studies report complete …

The optimal practice of medicine includes integrating individual clinical expertise with the
best available clinical evidence from systematic research. This article reviews nine treatment …

Oxygen is an important factor for wound healing. Although several different therapies
investigated the use of oxygen to aid wound healing, the results of these studies are not …