Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Molecularly engineered room-temperature phosphorescence for biomedical application: from the visible toward second near-infrared window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles

J Li, Y Luo, Z Zeng, D Cui, J Huang, C Xu, L Li… - Nature …, 2022 - nature.com
Nanomedicine holds promise to enhance cancer immunotherapy; however, its potential to
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …

Chemiluminescence for bioimaging and therapeutics: recent advances and challenges

M Yang, J Huang, J Fan, J Du, K Pu… - Chemical Society Reviews, 2020 - pubs.rsc.org
Chemiluminescence, the generation of light through chemiexcitation as a result of chemical
reactions, has emerged as a novel tool for bioimaging and therapy in vivo. Due to the …

Preparation of AIEgen-based near-infrared afterglow luminescence nanoprobes for tumor imaging and image-guided tumor resection

C Chen, X Zhang, Z Gao, G Feng, D Ding - Nature Protocols, 2024 - nature.com
Fluorescence imaging represents a vital tool in modern biology, oncology and biomedical
applications. Afterglow luminescence (AGL), which circumvents the light scattering and …

Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging

J Huang, K Pu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Optical imaging plays a crucial role in biomedicine. However, due to strong light scattering
and autofluorescence in biological tissue between 650–900 nm, conventional optical …

Room‐temperature phosphorescence resonance energy transfer for construction of near‐infrared afterglow imaging agents

Q Dang, Y Jiang, J Wang, J Wang, Q Zhang… - Advanced …, 2020 - Wiley Online Library
Afterglow imaging that detects photons after cessation of optical excitation avoids tissue
autofluorescence and thus possesses higher sensitivity than traditional fluorescence …

Design and challenges of sonodynamic therapy system for cancer theranostics: from equipment to sensitizers

Z Gong, Z Dai - Advanced Science, 2021 - Wiley Online Library
As a novel noninvasive therapeutic modality combining low‐intensity ultrasound and
sonosensitizers, sonodynamic therapy (SDT) is promising for clinical translation due to its …