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Precision psychiatry and Research Domain Criteria: Implications for clinical trials and future practice
Psychiatric disorders are associated with significant social and economic burdens, many of
which are related to issues with current diagnosis and treatments. The coronavirus (COVID …
which are related to issues with current diagnosis and treatments. The coronavirus (COVID …
The dynamic interplay between puberty and structural brain development as a predictor of mental health difficulties in adolescence: A systematic review
S Kretzer, AJ Lawrence, R Pollard, X Ma, PJ Chen… - Biological …, 2024 - Elsevier
Puberty is a time of intense reorganization of brain structure and a high-risk period for the
onset of mental health problems, with variations in pubertal timing and tempo intensifying …
onset of mental health problems, with variations in pubertal timing and tempo intensifying …
Don't get lost in translation: Integrating developmental and implementation sciences to accelerate real-world impact on children's development, health, and wellbeing
Translation of developmental science discoveries is impeded by numerous barriers at
different stages of the research-to-practice pipeline. Actualization of the vast potential of the …
different stages of the research-to-practice pipeline. Actualization of the vast potential of the …
Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum
Features of autism spectrum disorder, attention‐deficit/hyperactivity disorder, learning
disorders, intellectual disabilities, and communication and motor disorders usually emerge …
disorders, intellectual disabilities, and communication and motor disorders usually emerge …
Developmental trajectories of irritability across the transition to toddlerhood: Associations with effortful control and psychopathology
Y Zhang, LA MacNeill, RC Edwards, JL Burns… - Research on Child and …, 2024 - Springer
Preschool-age irritability is a transdiagnostic marker of internalizing and externalizing
problems. However, researchers have generally been reluctant to examine irritability within …
problems. However, researchers have generally been reluctant to examine irritability within …
Predictive utility of irritability “in context”: Proof-of-principle for an early childhood mental health risk calculator
Objective We provide proof-of-principle for a mental health risk calculator advancing clinical
utility of the irritability construct for identification of young children at high risk for common …
utility of the irritability construct for identification of young children at high risk for common …
Prevalence, stability, and predictive utility of the Multidimensional Assessment of Preschoolers Scales clinically optimized irritability score: Pragmatic early assessment …
JL Wiggins, A Ureña Rosario… - … Journal of Methods …, 2023 - Wiley Online Library
Objectives Characterizing the scope and import of early childhood irritability is essential for
real‐world actualization of this reliable indicator of transdiagnostic mental health risk. Thus …
real‐world actualization of this reliable indicator of transdiagnostic mental health risk. Thus …
Current perspectives on perinatal mental health and neurobehavioral development: focus on regulation, coregulation and self-regulation
During the perinatal period, addressing vulnerable contexts and building resilient systems
may promote neurobehavioral development. A pluralistic approach to research, taking a …
may promote neurobehavioral development. A pluralistic approach to research, taking a …
Neurodevelopmental vulnerability to psychosis: Developmentally-based methods enable detection of early life inhibitory control deficits that predict psychotic-like …
BackgroundInhibitory control develops in early childhood, and atypical development may be
a measurable marker of risk for the later development of psychosis. Additionally, inhibitory …
a measurable marker of risk for the later development of psychosis. Additionally, inhibitory …
Pathways link environmental and genetic factors with structural brain networks and psychopathology in youth
A Qiu, C Liu - Neuropsychopharmacology, 2023 - nature.com
Adolescence is a period of significant brain development and maturation, and it is a time
when many mental health problems first emerge. This study aimed to explore a …
when many mental health problems first emerge. This study aimed to explore a …