Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides
The plasma membrane and the underlying cortical actin cytoskeleton undergo continuous
dynamic interplay that is responsible for many essential aspects of cell physiology …
dynamic interplay that is responsible for many essential aspects of cell physiology …
[HTML][HTML] Regulation of actin cytoskeleton dynamics in cells
SH Lee, R Dominguez - Molecules and cells, 2010 - Elsevier
The dynamic remolding of the actin cytoskeleton is a critical part of most cellular activities,
and malfunction of cytoskeletal proteins results in various human diseases. The transition …
and malfunction of cytoskeletal proteins results in various human diseases. The transition …
Mechanisms of actin disassembly and turnover
Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …
their biological roles. Once assembled, these filamentous networks are either maintained in …
Cap** protein regulators fine-tune actin assembly dynamics
Cap** protein (CP) binds the fast growing barbed end of the actin filament and regulates
actin assembly by blocking the addition and loss of actin subunits. Recent studies provide …
actin assembly by blocking the addition and loss of actin subunits. Recent studies provide …
The yeast actin cytoskeleton: from cellular function to biochemical mechanism
JB Moseley, BL Goode - Microbiology and Molecular Biology …, 2006 - Am Soc Microbiol
All cells undergo rapid remodeling of their actin networks to regulate such critical processes
as endocytosis, cytokinesis, cell polarity, and cell morphogenesis. These events are driven …
as endocytosis, cytokinesis, cell polarity, and cell morphogenesis. These events are driven …
MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11
J Bockhorn, R Dalton, C Nwachukwu, S Huang… - Nature …, 2013 - nature.com
Chemotherapy resistance frequently drives tumour progression. However, the underlying
molecular mechanisms are poorly characterized. Epithelial-to-mesenchymal transition has …
molecular mechanisms are poorly characterized. Epithelial-to-mesenchymal transition has …
Regulation of cytoskeletal dynamics by actin-monomer-binding proteins
The actin cytoskeleton is a vital component of several key cellular and developmental
processes in eukaryotes. Many proteins that interact with filamentous and/or monomeric …
processes in eukaryotes. Many proteins that interact with filamentous and/or monomeric …
miR-206 inhibits stemness and metastasis of breast cancer by targeting MKL1/IL11 pathway
Purpose: Effective targeting of cancer stem cells is necessary and important for eradicating
cancer and reducing metastasis-related mortality. Understanding of cancer stemness …
cancer and reducing metastasis-related mortality. Understanding of cancer stemness …
Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy
Q Li, XW Song, J Zou, GK Wang… - Journal of cell …, 2010 - journals.biologists.com
MicroRNAs are involved in several aspects of cardiac hypertrophy, including cardiac growth,
conduction, and fibrosis. However, their effects on the regulation of the cardiomyocyte …
conduction, and fibrosis. However, their effects on the regulation of the cardiomyocyte …
Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks
Coordinated polymerization of actin filaments provides force for cell migration,
morphogenesis and endocytosis. Cap** protein (CP) is a central regulator of actin …
morphogenesis and endocytosis. Cap** protein (CP) is a central regulator of actin …