How does cognition regulate innate behaviors? While the cognitive functions of the cortex
have been extensively studied, we know much less about how cognition can regulate innate …

The hippocampus and its extended network contribute to encoding and recall of episodic
experiences. Drawing from recent anatomical, physiological, and behavioral studies, we …

In humans, traumatic social experiences can contribute to psychiatric disorders. It is
suggested that social trauma impairs brain reward function such that social behaviour is no …

Although bile acids play a notable role in depression, the pathological significance of the
bile acid TGR5 membrane-type receptor in this disorder remains elusive. Using depression …

Major depressive disorder ranks as a major burden of disease worldwide, yet the current
antidepressant medications are limited by frequent non-responsiveness and significant side …

Septal-hypothalamic neuronal activity centrally mediates aggressive behavior and
dopamine system hyperactivity is associated with elevated aggression. However, the causal …

The ventral hippocampus (vHPC) is a critical hub in networks that process emotional
information. While recent studies have indicated that ventral CA1 (vCA1) projection neurons …

The lateral septum (LS) is implicated as a hub that regulates a variety of affects, such as
reward, feeding, anxiety, fear, sociability, and memory. However, it remains unclear how the …

Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of
which have been only partially elucidated. The hippocampus serves as a major target of …

Adult hippocampal neurogenesis (AHN) represents a remarkable form of neuroplasticity that
has increasingly been linked to the stress response in recent years. However, the …