Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y **a - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Comparative analysis of core microbiome assignments: implications for ecological synthesis

GF Custer, M Gans, LTA van Diepen, F Dini-Andreote… - Msystems, 2023 - journals.asm.org
The concept of a core microbiome has been broadly used to refer to the consistent presence
of a set of taxa across multiple samples within a given habitat. The assignment of taxa to …

[HTML][HTML] PyMC: a modern, and comprehensive probabilistic programming framework in Python

O Abril-Pla, V Andreani, C Carroll, L Dong… - PeerJ Computer …, 2023 - peerj.com
PyMC is a probabilistic programming library for Python that provides tools for constructing
and fitting Bayesian models. It offers an intuitive, readable syntax that is close to the natural …

sccomp: Robust differential composition and variability analysis for single-cell data

S Mangiola, AJ Roth-Schulze, M Trussart… - Proceedings of the …, 2023 - pnas.org
Cellular omics such as single-cell genomics, proteomics, and microbiomics allow the
characterization of tissue and microbial community composition, which can be compared …

High-resolution population estimation using household survey data and building footprints

G Boo, E Darin, DR Leasure, CA Dooley… - Nature …, 2022 - nature.com
The national census is an essential data source to support decision-making in many areas
of public interest. However, this data may become outdated during the intercensal period …

The quest for absolute abundance: The use of internal standards for DNA‐based community ecology

JG Harrison, W John Calder, B Shuman… - Molecular Ecology …, 2021 - Wiley Online Library
To characterize microbiomes and other ecological assemblages, ecologists routinely
sequence and compare loci that differ among focal taxa. Counts of these sequences convey …

Evidence supportive of a bacterial component in the etiology for Alzheimer's disease and for a temporal-spatial development of a pathogenic microbiome in the brain

Y Moné, JP Earl, JE Król, A Ahmed, B Sen… - Frontiers in cellular …, 2023 - frontiersin.org
Background Over the last few decades, a growing body of evidence has suggested a role for
various infectious agents in Alzheimer's disease (AD) pathogenesis. Despite diverse …

The gut microbiome reflects ancestry despite dietary shifts across a hybrid zone

DP Nielsen, JG Harrison, NW Byer, TM Faske… - Ecology …, 2023 - Wiley Online Library
The microbiome is critical to an organism's phenotype, and its composition is shaped by,
and a driver of, eco‐evolutionary interactions. We investigated how host ancestry, habitat …

Host immunity alters community ecology and stability of the microbiome in a Caenorhabditis elegans model

M Taylor, NM Vega - Msystems, 2021 - journals.asm.org
ABSTRACT A growing body of data suggests that the microbiome of a species can vary
considerably from individual to individual, but the reasons for this variation—and the …

Compositional data analysis enables statistical rigor in comparative glycomics

AR Bennett, J Lundstrøm, S Chatterjee… - Nature …, 2025 - nature.com
Comparative glycomics data are compositional data, where measured glycans are parts of a
whole, indicated by relative abundances. Applying traditional statistical analyses to these …