The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

Coronavirus disease 2019 (COVID-19) is a viral infection caused by SARS-CoV-2 that
induces a generalized inflammatory state. Organokines (adipokines, osteokines, myokines …

Background Chemerin is an extracellular protein with chemotactic activities and its
expression is increased in various diseases such as metabolic syndrome and inflammatory …

Chemerin is a protein encoded by the Rarres2 gene that acts through endocrine or
paracrine regulation. Chemerin can bind to its receptor, regulate insulin sensitivity and …

In the 2 years since the COVID‐19 pandemic was officially declared, science has made
considerable strides in understanding the disease's pathophysiology, pharmacological …

The rapid development of vaccines to combat severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infections has been critical to reduce the severity of COVID-19 …

Adipose tissue is actually regarded as an endocrine organ, rather than as an organ that
merely stores energy. During the COVID-19 pandemic, obesity has undoubtedly emerged as …

Abstract Obesity, type 2 diabetes (T2DM), hypertension (HTN), and Cardiovascular Disease
(CVD) often cluster together as “Cardiometabolic Disease”(CMD). Just under 50% of …

Omentin (intelectin) was first detected in the visceral omental adipose tissue. It has mainly
two isoforms, omentin-1 and-2, with isoform-1 being the main form in human blood. It …

SARS-CoV-2 shows a high affinity for the ACE-2 receptor, present on the epithelial cells of
the upper and lower respiratory tract, within the intestine, kidneys, heart, testes, biliary …