Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed,
inflammatory mediators likely link many traditional and emerging risk factors with …

OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …

Atherosclerotic Plaque Healing Atherosclerotic plaque rupture and erosion result in acute
coronary syndromes. Plaque healing after initial disruption has been less extensively …

The leading cause of heart disease in developed countries is coronary atherosclerosis,
which is not simply a result of ageing but a chronic inflammatory process that can lead to …

Optical coherence tomography (OCT) has been increasingly utilised to guide percutaneous
coronary intervention (PCI). Despite the diagnostic utility of OCT, facilitated by its high …

Current algorithms for assessing risk of atherosclerotic cardiovascular disease (ASCVD)
and, in particular, the reliance on low-density lipoprotein (LDL) cholesterol in conditions …

Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite
current therapeutic developments, there is an unmet necessity in the prevention of …

Background The clinical value of high-risk coronary plaque characteristics (CPCs) to inform
intensified medical therapy or revascularization of non–flow-limiting lesions remains …