Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives

M Bauer, OA Andreassen, JR Geddes… - The Lancet …, 2018 - thelancet.com
This Review discusses crucial areas related to the identification, clinical presentation,
course, and therapeutic management of bipolar disorder, a major psychiatric illness. Bipolar …

What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group

CRK Ching, DP Hibar, TP Gurholt, A Nunes… - Human brain …, 2022 - Wiley Online Library
MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for …

LN Yatham, SH Kennedy, SV Parikh… - Bipolar …, 2013 - Wiley Online Library
Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Beaulieu S, Alda M, O'Donovan C,
MacQueen G, McIntyre RS, Sharma V, Ravindran A, Young LT, Milev R, Bond DJ, Frey BN …

[HTML][HTML] Psychotic symptoms in bipolar disorder and their impact on the illness: a systematic review

S Chakrabarti, N Singh - World journal of psychiatry, 2022 - ncbi.nlm.nih.gov
BACKGROUND Lifetime psychotic symptoms are present in over half of the patients with
bipolar disorder (BD) and can have an adverse effect on its course, outcome, and treatment …

Borderline personality disorder and bipolar affective disorder. Spectra or spectre? A review

D Bassett - Australian & New Zealand Journal of Psychiatry, 2012 - journals.sagepub.com
Objective: Bipolar affective disorder and borderline personality disorder have long been
considered to have significant similarities and comorbidity. This review endeavours to clarify …

Functional outcome in bipolar disorder: the big picture

B Levy, E Manove - Depression research and treatment, 2012 - Wiley Online Library
Previous research on functional outcome in bipolar disorder (BD) has uncovered various
factors that exacerbate psychosocial disability over the course of illness, including genetics …

Neuroprogression and episode recurrence in bipolar I disorder: a study of gray matter volume changes in first‐episode mania and association with clinical outcome

JM Kozicky, A McGirr, DJ Bond, M Gonzalez… - Bipolar …, 2016 - Wiley Online Library
Objectives Bipolar I disorder (BD‐I) is associated with gray matter volume (GMV) alterations
in neural regions important for emotional regulation. Reductions found in patients with …

Three‐year longitudinal cognitive functioning in patients recently diagnosed with bipolar disorder

IJ Torres, H Qian, J Basivireddy… - Acta Psychiatrica …, 2020 - Wiley Online Library
Objective The longitudinal course of neuropsychological functioning after the first manic
episode in bipolar disorder is unknown. The present study evaluated cognitive change in …

Inflammatory cytokines and cognitive functioning in early-stage bipolar I disorder

T Chakrabarty, IJ Torres, DJ Bond… - Journal of affective …, 2019 - Elsevier
Background Increased circulating inflammatory cytokines is a replicated finding in bipolar I
disorder (BDI). Pro-inflammatory cytokines such as TNFα, IL-6 and IL-1 have also been …

Lithium for the maintenance treatment of bipolar I disorder: a double-blind, placebo-controlled discontinuation study

RL Findling, NK McNamara, M Pavuluri… - Journal of the American …, 2019 - Elsevier
Objective This study examined the role of lithium in the maintenance treatment of pediatric
patients with bipolar I disorder (BP-I). Method Participants aged 7 to 17 years who presented …