Purpose Critically ill patients, among whom acute kidney injury is common, are often
considered particularly vulnerable to iodinated contrast medium nephrotoxicity. However …

Contrast-induced acute kidney injury (CI-AKI) is a problem associated with the use of
iodinated contrast media, causing kidney dysfunction in patients with preexisting renal …

Chronic kidney disease (CKD) is a global health problem characterized by progressive renal
fibrosis and excessive extracellular matrix deposition. Oxidative stress and epigenetic …

Our study aimed to conduct a comprehensive biochemical profiling and metabolomics
analysis to investigate the effects of arsenic-induced metabolic disorders, with a specific …

Oxidative stress plays an important role in the pathophysiology of acute kidney injury (AKI).
Previously, we reported that vanin-1, which is involved in oxidative stress, is associated with …

The target of this study was to estimate Gum Arabic for total phenols and flavonoids. In
addition to antioxidant activities, estimate gum Arabic for total phenols and flavonoids. In …

In 2011, the US Food and drug Administration (FDA) developed a strategic plan for
regulatory science that focuses on develo** new tools, standards, and approaches to …

Nickel exposure is known to induce oxidative stress and inflammation and disrupt critical
metabolic pathways, leading to hepatic dysfunction and impaired glucose regulation. This …

The present study aimed to investigate the beneficial effects of the treatment with extracts
from the edible mushroom Lactarius deterrimus (Ld) and the chestnut Castanea sativa (Cs) …

The development of novel safety or efficacy biomarkers has increasingly been used to
improve safety monitoring and minimize attrition during drug development; however, for new …