Structural modifications of amino acid sequences of radiolabeled peptides for targeted tumor imaging
Molecular imaging techniques are increasingly being used in localization, staging and
therapy control of cancer. Due to their unique target specificity for the endogenous receptors …
therapy control of cancer. Due to their unique target specificity for the endogenous receptors …
Monoclonal antibody conjugated magnetic nanoparticles could target MUC‐1‐positive cells in vitro but not in vivo
MUC1 antigen is recognized as a high‐molecular‐weight glycoprotein that is unexpectedly
over‐expressed in human breast and other carcinomas. In contrast, C595 a monoclonal …
over‐expressed in human breast and other carcinomas. In contrast, C595 a monoclonal …
Estimated background doses of [67Ga]-DTPA-USPIO in normal Balb/c mice as a potential therapeutic agent for liver and spleen cancers
Methods Ultrasmall superparamagnetic iron oxide (USPIO) was successively labeled with
67 Ga-chloride after chelation with freshly prepared cyclic DTPA-dianhydride. The labeling …
67 Ga-chloride after chelation with freshly prepared cyclic DTPA-dianhydride. The labeling …
Comparison of estimated human effective dose of 67Ga- and 99mTc-labeled bombesin based on distribution data in mice
This study describes the preparation, biodistribution and absorbed dose prediction of 67 Ga
and 99m Tc labeled bombesin (BBN) in human organs, after injection in mice determined …
and 99m Tc labeled bombesin (BBN) in human organs, after injection in mice determined …
Comparison of estimated human dose of 68Ga-MAA with 99mTc-MAA based on rat data
Objective 99m Tc macroaggregated albumin (99m Tc-MAA) that had been used as a
perfusion agent has been evaluated. In this study, we tried to estimate human absorbed …
perfusion agent has been evaluated. In this study, we tried to estimate human absorbed …
Estimated human absorbed dose for 68Ga-ECC based on mice data: comparison with 67Ga-ECC
Objective Nowadays, the efficacies of 68 Ga-based tracers are comparable to that of 18 F-
based agents and have stimulated researchers to investigate the potential of 68 Ga-based …
based agents and have stimulated researchers to investigate the potential of 68 Ga-based …
Automated radiosynthesis and preclinical evaluation of Al [18F] F-NOTA-P-GnRH for PET imaging of GnRH receptor-positive tumors
S Huang, H Wu, B Li, L Fu, P Sun, M Wang… - Nuclear Medicine and …, 2020 - Elsevier
Abstract Introduction Gonadotropin releasing hormone (GnRH) receptor is overexpressed in
many human tumors. Previously we developed a 18 F-labelled GnRH peptide. Although the …
many human tumors. Previously we developed a 18 F-labelled GnRH peptide. Although the …
Estimated human absorbed dose of 177Lu–BPAMD based on mice data: Comparison with 177Lu–EDTMP
In this work, the absorbed dose of human organs for 177 Lu–BPAMD was evaluated based
on biodistribution studies into the Syrian mice by RADAR method and was compared with …
on biodistribution studies into the Syrian mice by RADAR method and was compared with …
Biodistribution evaluation of 166Ho–DTPA–SPION in normal rats
Super paramagnetic iron oxide nanoparticles (SPION) with a cross-linked dextran coating
can be used as a negative contrast agent in magnetic resonance imaging agent. This study …
can be used as a negative contrast agent in magnetic resonance imaging agent. This study …
Internal dosimetry studies of 177Lu-BBN-GABA-DOTA, as a cancer therapy agent, in human tissues based on animal data
The goal of using radiopharmaceuticals for therapeutic purposes is twofold: first, the most
damage to cancer cells and, second, the most negligible dose transfers to healthy tissues …
damage to cancer cells and, second, the most negligible dose transfers to healthy tissues …