Baeyer− Villiger monooxygenases: more than just green chemistry

H Leisch, K Morley, PCK Lau - Chemical reviews, 2011 - ACS Publications
What is life without oxygen is a rhetorical question. On the other hand, unraveling the
intricacies and understanding the various mechanisms underpinning the biological …

Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts

WJH Van Berkel, NM Kamerbeek, MW Fraaije - Journal of biotechnology, 2006 - Elsevier
During the last decades a large number of flavin-dependent monooxygenases have been
isolated and studied. This has revealed that flavoprotein monooxygenases are able to …

Enantioselective enzymatic desymmetrizations in organic synthesis

E García-Urdiales, I Alfonso, V Gotor - Chemical Reviews, 2005 - ACS Publications
During the recent past years, tremendous efforts have been made to establish
enantioselective routes for the preparation of enantiomerically pure compounds due to their …

[PDF][PDF] N-Heterocyclic carbene catalyzed [4+ 3] annulation of enals and o-quinone methides: highly enantioselective synthesis of benzo-ε-lactones

H Lv, WQ Jia, LH Sun, S Ye - Angew. Chem. Int. Ed, 2013 - academia.edu
Hui Lv, Wen-Qiang Jia, Li-Hui Sun, and Song Ye* e-Lactones are privileged motifs occurring
in a wide variety of biologically active natural and unnatural products.[1] Therefore, the …

Recent developments in the application of Baeyer–Villiger monooxygenases as biocatalysts

G de Gonzalo, MD Mihovilovic, MW Fraaije - ChemBioChem, 2010 - Wiley Online Library
Abstract Baeyer–Villiger monooxygenases (BVMOs) represent a specific class of
monooxygenases that are capable of catalyzing a variety of oxidation reactions, including …

[PDF][PDF] Bacteria incorporation in deep-eutectic solvents through freeze-drying

MC Gutiérrez, ML Ferrer, L Yuste, F Rojo… - Angew. Chem, 2010 - academia.edu
Biocatalysis (based on either enzymes or whole microorganisms) has matured to a standard
technology in the finechemicals industry, as reflected in the number of biotransformation …

Baeyer-Villiger oxidations: biotechnological approach

M Bučko, P Gemeiner, A Schenkmayerová… - Applied microbiology …, 2016 - Springer
Abstract Baeyer-Villiger monooxygenases (BVMOs) are a very well-known and intensively
studied class of flavin-dependent enzymes. Their substrate promiscuity, high chemo-, regio …

[PDF][PDF] Self-sufficient Baeyer-Villiger monooxygenases: effective coenzyme regeneration for biooxygenation by fusion engineering

DET Pazmiño, R Snajdrova, BJ Baas… - Angewandte Chemie …, 2008 - research.rug.nl
Over the past few years, industrial interest in biocatalysts that perform selective oxidative
reactions has increased significantly.[1] Baeyer–Villiger monooxygenases (BVMOs) have …

Enantioselective desymmetrization of cyclobutanones: a speedway to molecular complexity

J Sietmann, JM Wahl - Angewandte Chemie International …, 2020 - Wiley Online Library
Cyclobutanones hold a privileged role in enantioselective desymmetrization because their
inherent ring strain allows for a variety of unusual reactions to occur. Current strategies …

Enzyme mediated Baeyer-Villiger oxidations

MD Mihovilovic - Current Organic Chemistry, 2006 - ingentaconnect.com
Oxygenation reactions of ketones to esters are referred to as Baeyer-Villiger oxidations and
represent a powerful methodology in synthesis to break carbon-carbon bonds in an oxygen …