Pathology, diagnostics, and classification of medulloblastoma
BA Orr - Brain Pathology, 2020 - Wiley Online Library
Medulloblastoma (MB) is the most common CNS embryonal tumor. While the overall cure
rate is around 70%, patients with high‐risk disease continue to have poor outcome and …
rate is around 70%, patients with high‐risk disease continue to have poor outcome and …
2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist
The fifth edition of the World Health Organization Classification of Tumours of the Central
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …
Unified rhombic lip origins of group 3 and group 4 medulloblastoma
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into
biologically distinct subgroups, suggesting that a personalized approach to therapy would …
biologically distinct subgroups, suggesting that a personalized approach to therapy would …
MRI radiogenomics of pediatric medulloblastoma: a multicenter study
Background Radiogenomics of pediatric medulloblastoma (MB) offers an opportunity for MB
risk stratification, which may aid therapeutic decision making, family counseling, and …
risk stratification, which may aid therapeutic decision making, family counseling, and …
National Cancer Institute workshop on proton therapy for children: considerations regarding brainstem injury
Purpose Proton therapy can allow for superior avoidance of normal tissues. A widespread
consensus has been reached that proton therapy should be used for patients with curable …
consensus has been reached that proton therapy should be used for patients with curable …
MR imaging–based radiomic signatures of distinct molecular subgroups of medulloblastoma
BACKGROUND AND PURPOSE: Distinct molecular subgroups of pediatric
medulloblastoma confer important differences in prognosis and therapy. Currently, tissue …
medulloblastoma confer important differences in prognosis and therapy. Currently, tissue …
Pediatric brain tumor genetics: what radiologists need to know
Brain tumors are the most common solid tumors in the pediatric population. Pediatric neuro-
oncology has changed tremendously during the past decade owing to ongoing genomic …
oncology has changed tremendously during the past decade owing to ongoing genomic …
Advancing presurgical non-invasive molecular subgroup prediction in medulloblastoma using artificial intelligence and MRI signatures
Global investigation of medulloblastoma has been hindered by the widespread
inaccessibility of molecular subgroup testing and paucity of data. To bridge this gap, we …
inaccessibility of molecular subgroup testing and paucity of data. To bridge this gap, we …
Childhood malignant brain tumors: balancing the bench and bedside
C Thorbinson, JP Kilday - Cancers, 2021 - mdpi.com
Simple Summary Brain tumors remain the most common childhood solid tumors, accounting
for approximately 25% of all pediatric cancers. They also represent the most common cause …
for approximately 25% of all pediatric cancers. They also represent the most common cause …
Radiomic features from multi-parameter MRI combined with clinical parameters predict molecular subgroups in patients with medulloblastoma
The 2016 WHO classification of central nervous system tumors has included four molecular
subgroups under medulloblastoma (MB) as sonic hedgehog (SHH), wingless (WNT), Grade …
subgroups under medulloblastoma (MB) as sonic hedgehog (SHH), wingless (WNT), Grade …