A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Subcellular targeting strategies for protein and peptide delivery

H Su, G Rong, L Li, Y Cheng - Advanced Drug Delivery Reviews, 2024 - Elsevier
Cytosolic delivery of proteins and peptides provides opportunities for effective disease
treatment, as they can specifically modulate intracellular processes. However, most of …

Tandem Guest‐Host‐Receptor Recognitions Precisely Guide Ciprofloxacin to Eliminate Intracellular Staphylococcus aureus

W Zhan, L Xu, Z Liu, X Liu, G Gao, T **a… - Angewandte Chemie …, 2023 - Wiley Online Library
Staphylococcus aureus (S. aureus) is able to hide within host cells to escape immune
clearance and antibiotic action, causing life‐threatening infections. To boost the therapeutic …

Synthetic nanoassemblies for regulating organelles: from molecular design to precision therapeutics

Y Guo, P Li, X Guo, C Yao, D Yang - ACS nano, 2024 - ACS Publications
Each organelle referring to a complex multiorder architecture executes respective biological
processes via its distinct spatial organization and internal microenvironment. As the …

Enzymatic Dimerization‐Induced Self‐Assembly of Alanine‐Tyramine Conjugates into Versatile, Uniform, Enzyme‐Loaded Organic Nanoparticles

M Kumar Pradhan… - Angewandte …, 2024 - Wiley Online Library
Herein, we report a novel enzymatic dimerization‐induced self‐assembly (e‐DISA)
procedure that converts alanine‐tyramine conjugates into highly uniform enzyme‐loaded …

Latest advances in specific inhibition of tumor-associated carbonic anhydrases

CT Supuran - Future Medicinal Chemistry, 2023 - Taylor & Francis
Carbonic anhydrases (CAs; EC 4.2. 1.1) constitute a rather ancient class of enzymes that act
as highly efficient catalysts for the reversible hydration of CO2 to bicarbonate and protons …

[HTML][HTML] Self-assembly inside cellular organelles: Aspects of functions and various strategies for cancer therapy

S Kim, H Choi, S **, S Son, Y Lee, K Kim, JH Ryu - Giant, 2023 - Elsevier
Self-assembly generates three-dimensional architectures through the non-covalent
interactions of building blocks of various sizes, ranging from nanometers to micrometers …

Fibroblast Growth Factor Receptor 1-Specific Dehydrogelation to Release Its Inhibitor for Enhanced Lung Tumor Therapy

R Tang, Z Zhang, X Liu, L Zhu, Y Xu, R Chai, W Zhan… - ACS …, 2024 - ACS Publications
Fibroblast growth factor receptor 1 (FGFR1) is emerging as a promising molecular target of
lung cancer, and various FGFR1 inhibitors have exhibited significant therapeutic effects on …

A Membrane‐Anchoring Self‐Assembling Peptide Allows Bioorthogonal Coupling of Type‐I AIEgens for Pyroptosis‐Induced Cancer Therapy

S Ji, T Pan, K Wang, W Zai, R Jia… - Angewandte Chemie …, 2025 - Wiley Online Library
Enrichment of photosensitizers (PSs) on cancer cell membranes via bioorthogonal reactions
is considered to be a very promising therapeutic modality. However, azide‐modified sugars …

[HTML][HTML] In situ supramolecular self-assembly for alleviating multidrug resistance in cancer

J Zhao, X Wu, J Chen, C Wu, R Zhang, Q Yao… - Supramolecular …, 2023 - Elsevier
Drug resistance is one of the major causes of cancer treatment failures. In recent years, to
combat the issue of drug resistance, a large volume of strategies has been established …