Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with
significant morbidity and mortality. Managing risk of stroke and AF burden are pillars of AF …

Cine magnetic resonance imaging (MRI) is the current gold standard for the assessment of
cardiac anatomy and function. However, it typically only acquires a set of two-dimensional …

Human cardiac function is characterized by a complex interplay of mechanical deformation
and electrophysiological conduction. Similar to the underlying cardiac anatomy, these …

Cardiac anatomy and function vary considerably across the human population with
important implications for clinical diagnosis and treatment planning. Consequently, many …

Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac
function in a non-invasive manner, making them a promising approach for personalized …

Numerical simulations of cardiovascular device deployment within digital twins of patient-
specific anatomy can expedite and de-risk the device design process. Nonetheless, the …

Patient-specific cardiac computational models are essential for the efficient realization of
precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can …

Understanding population-wide variability of the human heart is crucial to detect
abnormalities and improve the assessment of both cardiac anatomy and function. While …

Global single-valued biomarkers, such as ejection fraction, are widely used in clinical
practice to assess cardiac function. However, they only approximate the heart's true 3D …

Myocardial infarction (MI) is one of the most common causes of death in the world. Image-
based biomarkers commonly used in the clinic, such as ejection fraction, fail to capture more …