Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Premature ovarian insufficiency (POI) is a major cause of female infertility due to early loss of
ovarian function. POI is a heterogeneous condition, and its molecular etiology is unclear. To …

Endocrine disrupting chemicals (EDCs) are ubiquitous in aquatic and terrestrial
environments. The main objective of this review was to summarize the current knowledge of …

Key Clinical Points Primary Ovarian Insufficiency Primary ovarian insufficiency should be
considered in women younger than 40 years of age who present with new-onset irregular …

Objective The objective of this review was to answer the global prevalence of premature
ovarian insufficiency (POI), and explore the associated factors including etiopathology and …

BACKGROUND The early onset of menopause is associated with increased risks of
cardiovascular disease and osteoporosis. As a woman's circulating anti-Müllerian hormone …

Background Early menopause is linked to an increased risk of cardiovascular disease
mortality; however, the association between early menopause and incidence and timing of …

Women spend approximately one-third of their lives with menopause, which occurs around
50 years of age. It is now appreciated that several important metabolic and cardiovascular …

The aim of this International Menopause Society White Paper on premature ovarian
insufficiency (POI) is to provide the latest information regarding this distressing condition …