Mammalian cortical networks are active before synaptogenesis begins in earnest, before
neuronal migration is complete, and well before an animal opens its eyes and begins to …

The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …

The ability to form precise, episodic memories develops with age, with young children only
able to form gist-like memories that lack precision. The cellular and molecular events in the …

It is often thought that the construction of cortical circuits occurs as the result of an elegantly
designed process that unfolds sequentially as an animal develops until adult functional …

The prefrontal cortex is considered as the site of multifaceted higher-order cognitive abilities.
These abilities emerge late in life long after full sensorimotor maturation, in line with the …

Significance The function of the hippocampus in behavior and cognition has long been
studied primarily through electrophysiological recordings from freely moving rodents …

GABAergic signaling provides inhibitory stabilization and spatiotemporally coordinates the
firing of recurrently connected excitatory neurons in mature cortical circuits. Inhibition thus …

Sharp wave-ripples (SPW-Rs) are a hippocampal network phenomenon critical for memory
consolidation and planning. SPW-Rs have been extensively studied in the adult brain, yet …

Develo** neural circuits show unique patterns of spontaneous activity and structured
network connectivity shaped by diverse activity-dependent plasticity mechanisms. Based on …

Early Sharp Waves (eSPWs) are the earliest pattern of network activity in the develo**
hippocampus of neonatal rodents. eSPWs were originally considered to be an immature …