Intranasal vaccine: Factors to consider in research and development
Most existing vaccines for human use are administered by needle-based injection.
Administering vaccines needle-free intranasally has numerous advantages over by needle …
Administering vaccines needle-free intranasally has numerous advantages over by needle …
[PDF][PDF] Liposomal drug delivery: a versatile platform for challenging clinical applications
Liposomes are lipid based vesicular systems that offer novel platform for versatile drug
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
Mucosal vaccination via the respiratory tract
M Hellfritzsch, R Scherließ - Pharmaceutics, 2019 - mdpi.com
Vaccine delivery via mucosal surfaces is an interesting alternative to parenteral vaccine
administration, as it avoids the use of a needle and syringe. Mucosal vaccine administration …
administration, as it avoids the use of a needle and syringe. Mucosal vaccine administration …
Lipid-based particles: versatile delivery systems for mucosal vaccination against infection
B Corthésy, G Bioley - Frontiers in immunology, 2018 - frontiersin.org
Vaccination is the process of administering immunogenic formulations in order to induce or
harness antigen (Ag)-specific antibody and T cell responses in order to protect against …
harness antigen (Ag)-specific antibody and T cell responses in order to protect against …
Recent advances in respiratory immunization: A focus on COVID-19 vaccines
X He, X Chen, H Wang, G Du, X Sun - Journal of Controlled Release, 2023 - Elsevier
The development of vaccines has always been an essential task worldwide since vaccines
are regarded as powerful weapons in protecting the global population. Although the vast …
are regarded as powerful weapons in protecting the global population. Although the vast …
Induction of protective immune responses at respiratory mucosal sites
SC Park, MJ Wiest, V Yan, PT Wong… - Human Vaccines & …, 2024 - Taylor & Francis
Many pathogens enter the host through mucosal sites. Thus, interfering with pathogen entry
through local neutralization at mucosal sites therefore is an effective strategy for preventing …
through local neutralization at mucosal sites therefore is an effective strategy for preventing …
Carbohydrate immune adjuvants in subunit vaccines
Modern subunit vaccines are composed of antigens and a delivery system and/or adjuvant
(immune stimulator) that triggers the desired immune responses. Adjuvants mimic pathogen …
(immune stimulator) that triggers the desired immune responses. Adjuvants mimic pathogen …
Intranasal formulations: promising strategy to deliver vaccines
P Riese, P Sakthivel, S Trittel… - Expert opinion on drug …, 2014 - Taylor & Francis
Introduction: The emergence of new diseases and the lack of efficient vaccines against
numerous nontreatable pathogens require the development of novel vaccination strategies …
numerous nontreatable pathogens require the development of novel vaccination strategies …
Leukemia inhibitory factor protects the lung during respiratory syncytial viral infection
RF Foronjy, AJ Dabo, N Cummins, P Geraghty - BMC immunology, 2014 - Springer
Background Respiratory syncytial virus (RSV) infects the lung epithelium where it stimulates
the production of numerous host cytokines that are associated with disease burden and …
the production of numerous host cytokines that are associated with disease burden and …
Nanoparticles for mucosal vaccine delivery
Mucosal surfaces represent important routes of entry into the human body for the majority of
pathogens, and they constitute unique sites for targeted vaccine delivery. Nanoparticle …
pathogens, and they constitute unique sites for targeted vaccine delivery. Nanoparticle …