Circular RNA: metabolism, functions and interactions with proteins
WY Zhou, ZR Cai, J Liu, DS Wang, HQ Ju, RH Xu - Molecular cancer, 2020 - Springer
Abstract Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules
that are ubiquitous across species ranging from viruses to mammals. Important advances …
that are ubiquitous across species ranging from viruses to mammals. Important advances …
Specific expression and functions of circular RNAs
In recent years, circular RNAs (circRNAs), a new class of RNA molecules characterized by
their covalently closed circular structure, have become a new research paradigm in RNA …
their covalently closed circular structure, have become a new research paradigm in RNA …
Exosome-derived circCCAR1 promotes CD8+ T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
Z Hu, G Chen, Y Zhao, H Gao, L Li, Y Yin, J Jiang… - Molecular cancer, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) can be encapsulated into exosomes to
participate in intercellular communication, affecting the malignant progression of a variety of …
participate in intercellular communication, affecting the malignant progression of a variety of …
[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
M6A-mediated upregulation of circMDK promotes tumorigenesis and acts as a nanotherapeutic target in hepatocellular carcinoma
A Du, S Li, Y Zhou, C Disoma, Y Liao, Y Zhang, Z Chen… - Molecular cancer, 2022 - Springer
Background Emerging evidence suggest the critical role of circular RNAs (circRNAs) in
disease development especially in various cancers. However, the oncogenic role of …
disease development especially in various cancers. However, the oncogenic role of …
[HTML][HTML] Circular RNA ACTN4 promotes intrahepatic cholangiocarcinoma progression by recruiting YBX1 to initiate FZD7 transcription
Q Chen, H Wang, Z Li, F Li, L Liang, Y Zou, H Shen… - Journal of …, 2022 - Elsevier
Background & Aims Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with
high aggressiveness and extremely poor prognosis. The role of circular RNAs (circRNAs) in …
high aggressiveness and extremely poor prognosis. The role of circular RNAs (circRNAs) in …
Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma
X Zhang, Y Xu, L Ma, K Yu, Y Niu, X Xu… - Cancer …, 2022 - Wiley Online Library
Background Resistance to ferroptosis, a regulated cell death caused by iron‐dependent
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …
Circular RNA vaccine induces potent T cell responses
Circular RNAs (circRNAs) are a class of RNAs commonly found across eukaryotes and
viruses, characterized by their resistance to exonuclease-mediated degradation. Their …
viruses, characterized by their resistance to exonuclease-mediated degradation. Their …
The functional roles of the circRNA/Wnt axis in cancer
CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …
[HTML][HTML] Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer
J Chen, Y Wu, X Luo, D **, W Zhou, Z Ju, D Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Tumor metastasis of colorectal cancer (CRC) is the main cause of death in
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …
most patients and the major difficulty in comprehensive CRC treatment. Circular RNAs …