Herpetic infections have plagued humanity for thousands of years, but only recently have
advances in antiviral medications and supportive treatments equipped physicians to combat …

A wide range of viruses from different virus families in different geographical areas, may
cause immediate or delayed neuropathological changes and neurological manifestations in …

Abstract The Stimulator of Interferon Genes (STING) pathway initiates potent immune
responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C …

Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can reach the brain
without evident clinical symptoms. Once in the central nervous system (CNS), the virus can …

This paper reviews the developments that have occurred in the field of human genetics of
infectious diseases from the second half of the 20th century onward. In particular, it stresses …

The investigation's goal was to obtain further knowledge about the connection between
Herpes Zoster infection and dentistry therapy for the osteonecrosis of the jaws, combining …

The etiologies of meningitis range in severity from benign and self-limited to life-threatening
with potentially severe morbidity. Bacterial meningitis is a medical emergency that requires …

The receptor-interacting kinase-3 (RIP3) and its downstream substrate mixed lineage kinase
domain-like protein (MLKL) have emerged as the key cellular components in programmed …

Senile amyloid plaques are one of the main hallmarks of Alzheimer's disease (AD). They
correspond to insoluble deposits of amyloid-ß peptides (Aß) and are responsible for the …

Herpes simplex virus type 1 (HSV-1) infection triggers a rapid induction of host innate
immune responses. The type I interferon (IFN) signal pathway is a central aspect of host …