Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of
quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years …

In the last two decades, DNA has attracted significant attention toward the development of
materials at the nanoscale for emerging applications due to the unparalleled versatility and …

Optimization of contrast-enhanced imaging and focused ultrasound therapy requires a
comprehensive understanding of in vivo microbubble (MB) pharmacokinetics. Prior studies …

Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …

As one of the most valuable endogenous gas signaling molecules, carbon monoxide (CO)
has been demonstrated in numerous studies to show excellent promise in the treatment of …

Radiation therapy (RT) causes DNA damage through ionization, leading to double-strand
breaks. In addition, it generates reactive oxygen species (ROS), which are toxic to tumor …

Blood scarcity is one of the main causes of healthcare disruptions worldwide, with blood
shortages occurring at an alarming rate. Over the last decades, blood substitutes have …

Currently, the response to cancer treatments is highly variable, and severe side effects and
toxicity are experienced by patients receiving high doses of chemotherapy, such as those …

Microbubbles (MBs) hold substantial promise for medical imaging and therapy; nonetheless,
knowledge gaps persist between composition, structure, and in vivo performance, especially …

In sonodynamic therapy, cellular toxicity from sonosensitizer drugs, such as 5-aminolevulinic
acid hydrochloride (5-ALA), may be triggered with focused ultrasound through the …