Why and how we age are 2 intertwined questions that have fascinated scientists for many
decades. However, attempts to answer these questions remain compartmentalized …

Anti-ageing biology and medicine programmes are a focus of genetics, molecular biology,
immunology, endocrinology, nutrition, and therapy. This paper discusses metabolic …

Male reproductive traits such as ejaculate size and quality, are expected to decline with
advancing age due to senescence. It is however unclear whether this expectation is upheld …

Patterns of ageing across the tree of life are much more diverse than previously thought. Yet,
we still do not adequately understand how, why and where across the tree of life a particular …

Most insects are poikilotherms and ectotherms, so their body temperature fluctuates and
closely aligns with the temperature of their environment. The rise in global temperatures is …

New biophysical theory and electronic databases raise the prospect of deriving fundamental
rules of life, a conceptual framework for how the structures and functions of molecules, cells …

Senescence patterns are highly variable across the animal kingdom. However, while
empirical evidence of actuarial senescence in vertebrates is accumulating in the wild and …

The body temperature of mosquitoes, like most insects, is dictated by the environmental
temperature. Climate change is increasing the body temperature of insects and thereby …

Reproductive performance typically improves with age, reaching a plateau at middle age
and subsequently declining in older age classes (senescing individuals). Three potential …

Daily light–dark cycles shape the circadian physiology and behaviour of nearly all
organisms, with variation in circadian phenotypes having cascading effects on individual …