Endophenotype best practices

WG Iacono, SM Malone, SI Vrieze - International Journal of …, 2017 - Elsevier
This review examines the current state of electrophysiological endophenotype research and
recommends best practices that are based on knowledge gleaned from the last decade of …

The causal influence of brain size on human intelligence: Evidence from within-family phenotypic associations and GWAS modeling

JJ Lee, M McGue, WG Iacono, AM Michael, CF Chabris - Intelligence, 2019 - Elsevier
There exists a moderate correlation between MRI-measured brain size and the general
factor of IQ performance (g), but the question of whether the association reflects a …

The accuracy of LD Score regression as an estimator of confounding and genetic correlations in genome‐wide association studies

JJ Lee, M McGue, WG Iacono… - Genetic epidemiology, 2018 - Wiley Online Library
To infer that a single‐nucleotide polymorphism (SNP) either affects a phenotype or is
linkage disequilibrium with a causal site, we must have some assurance that any SNP …

The association between saving disposition and financial distress: A genetically informed approach

A Giannelis, EA Willoughby, R Corley, C Hopfer… - Journal of Economic …, 2023 - Elsevier
Saving disposition, the tendency to save rather than consume, has been found to be
associated with economic outcomes. People lacking the disposition to save are more likely …

New insights into genetics underlying of plumage color

P Davoodi, A Ehsani, R Vaez Torshizi… - Animal …, 2022 - Wiley Online Library
Plumage color can be considered as a social signal in chickens and a breeding
identification tool among breeders. The relationship between plumage color and trait groups …

Simple PDMS microdevice for biomedical applications

C Potrich, L Lunelli, M Cocuzza, SL Marasso, CF Pirri… - Talanta, 2019 - Elsevier
Polydimethylsiloxane (PDMS) is a well-known biocompatible polymer employed for many
applications in the biomedical field. In this study, the biocompatibility and versatility of PDMS …

The genetics‐morphology‐behavior trifecta: Unraveling the single greatest limitation affecting our understanding of chondrichthyan evolution

JH Gayford - Ecology and Evolution, 2023 - Wiley Online Library
Sharks, rays, and chimaera form the clade Chondrichthyes, an ancient group of
morphologically and ecologically diverse vertebrates that has played an important role in …

From Genotype to Phenotype: polygenic prediction of complex human traits

TG Raben, L Lello, E Widen, SDH Hsu - Genomic Prediction of Complex …, 2022 - Springer
Decoding the genome confers the capability to predict characteristics of the organism
(phenotype) from DNA (genotype). We describe the present status and future prospects of …

Causal inference and GWAS: Rubin, Pearl, and Mendelian randomization

RJC Cantet, J Jensen - Journal of Animal Breeding and …, 2024 - Wiley Online Library
Abstract Although Genome Wide Analysis (GWAS) have been widely used to understand the
genetic architecture of complex quantitative traits, interpreting their results in terms of the …

LD Score regression as an estimator of confounding and genetic correlations in genome-wide association studies

JJ Lee, CC Chow - bioRxiv, 2017 - biorxiv.org
In order to infer that a single-nucleotide polymorphism (SNP) either affects a phenotype or is
linkage disequilibrium with a causal site, we must have some assurance that any SNP …