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Flavonoids: Overview of biosynthesis, biological activity, and current extraction techniques
Recently, increased attention has been paid to natural sources as raw materials for the
development of new added-value products. Flavonoids are a large family of polyphenols …
development of new added-value products. Flavonoids are a large family of polyphenols …
Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: from mechanisms to therapeutics
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …
discouragingly low survival rate and few effective treatments. An important function of the …
[HTML][HTML] CircRNAs: Pivotal modulators of TGF-β signalling in cancer pathogenesis
The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …
ncRNAs and their impact on dopaminergic neurons: autophagy pathways in Parkinson's disease
Parkinson's Disease (PD) is a complex neurological illness that causes severe motor and
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …
Polyphenol-loaded nano-carriers for breast cancer therapy: a comprehensive review
Breast cancer remains a significant global health challenge, demanding innovative
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …
Deciphering NF-kappaB pathways in smoking-related lung carcinogenesis
One of the main causes of death worldwide is lung cancer, which is largely caused by
cigarette smoking. The crucial transcription factor NF-κB, which controls inflammatory …
cigarette smoking. The crucial transcription factor NF-κB, which controls inflammatory …
Activated carbon-coated iron oxide magnetic nanocomposite (IONPs@ CtAC) loaded with morin hydrate for drug-delivery applications
Cancer is a major disease that affects millions of people around the world every year. It
affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer …
affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer …
[HTML][HTML] Therapeutic Potential of Natural Compounds to Modulate WNT/β-Catenin Signaling in Cancer: Current State of Art and Challenges
A Gajos-Michniewicz, M Czyz - International Journal of Molecular …, 2024 - mdpi.com
Targeted therapies and immunotherapies have improved the clinical outcome of cancer
patients; however, the efficacy of treatment remains frequently limited due to low …
patients; however, the efficacy of treatment remains frequently limited due to low …
Morin attenuates arsenic-induced toxicity in 3T3 embryonic fibroblast cells by suppressing oxidative stress, inflammation, and apoptosis: In vitro and silico evaluations
This study aims to investigate the curative effects of Morin, a flavonoid, against arsenic
toxicity in 3T3 embryonic fibroblast cells and its effect on the molecular mechanisms of cells …
toxicity in 3T3 embryonic fibroblast cells and its effect on the molecular mechanisms of cells …
Noncoding RNAs as therapeutic targets in autophagy-related diabetic cardiomyopathy
Diabetic cardiomyopathy, a multifaceted complication of diabetes mellitus, remains a major
challenge in clinical management due to its intricate pathophysiology. Emerging evidence …
challenge in clinical management due to its intricate pathophysiology. Emerging evidence …