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Glaucoma and the brain: trans-synaptic degeneration, structural change, and implications for neuroprotection
A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …
disease. The basis for this has been the finding of central nervous system changes in …
Glaucoma: a degenerative optic neuropathy related to neuroinflammation?
S Mélik Parsadaniantz, A Réaux-le Goazigo… - Cells, 2020 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness in the world and remains a
major public health problem. To date, incomplete knowledge of this disease's …
major public health problem. To date, incomplete knowledge of this disease's …
Structural brain abnormalities in patients with primary open-angle glaucoma: a study with 3T MR imaging
Purpose.: Weexamined changes of the central nervous system in patients with advanced
primary open-angle glaucoma (POAG). Methods.: The clinical observational study included …
primary open-angle glaucoma (POAG). Methods.: The clinical observational study included …
Structural and functional brain changes beyond visual system in patients with advanced glaucoma
P Frezzotti, A Giorgio, I Motolese, A De Leucio… - PloS one, 2014 - journals.plos.org
In order to test the hypothesis that in primary open angle glaucoma (POAG), an important
cause of irreversible blindness, a spreading of neurodegeneration occurs through the brain …
cause of irreversible blindness, a spreading of neurodegeneration occurs through the brain …
Changes of visual pathway and brain connectivity in glaucoma: a systematic review
R Nuzzi, L Dallorto, T Rolle - Frontiers in Neuroscience, 2018 - frontiersin.org
Background: Glaucoma is a leading cause of irreversible blindness worldwide. The
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …
Structural brain alterations in primary open angle glaucoma: a 3T MRI study
Glaucoma is not only an eye disease but is also associated with degeneration of brain
structures. We now investigated the pattern of visual and non-visual brain structural changes …
structures. We now investigated the pattern of visual and non-visual brain structural changes …
Early changes of brain connectivity in primary open angle glaucoma
P Frezzotti, A Giorgio, F Toto, A De Leucio… - Human Brain …, 2016 - Wiley Online Library
Our aim was to assess in primary open angle glaucoma (POAG), a major cause of
irreversible blindness worldwide, whether diffuse brain changes recently shown in …
irreversible blindness worldwide, whether diffuse brain changes recently shown in …
Residual vision activation and the brain-eye-vascular triad: Dysregulation, plasticity and restoration in low vision and blindness–a review
Vision loss due to ocular diseases such as glaucoma, optic neuropathy, macular
degeneration, or diabetic retinopathy, are generally considered an exclusive affair of the …
degeneration, or diabetic retinopathy, are generally considered an exclusive affair of the …
Disturbed spontaneous brain activity pattern in patients with primary angle-closure glaucoma using amplitude of low-frequency fluctuation: a fMRI study
X Huang, YL Zhong, XJ Zeng, F Zhou… - Neuropsychiatric …, 2015 - Taylor & Francis
Objective The aim of this study is to use amplitude of low-frequency fluctuation (ALFF) as a
method to explore the local features of spontaneous brain activity in patients with primary …
method to explore the local features of spontaneous brain activity in patients with primary …
Is there a link between open‐angle glaucoma and dementia? The Three‐City–Alienor Cohort
C Helmer, F Malet, MB Rougier… - Annals of …, 2013 - Wiley Online Library
Objective Previous research has suggested an association between dementia and
glaucoma through common risk factors or mechanisms. Our aim was to evaluate the …
glaucoma through common risk factors or mechanisms. Our aim was to evaluate the …