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In vitro anticancer activity of Eclipta alba whole plant extract on colon cancer cell HCT-116
Backgrounds Colon cancer is the third most deadly and one of the most diagnosed diseases
in the world. Although routine screening and early detection during last decades has …
in the world. Although routine screening and early detection during last decades has …
Regulation of Hsf1 and the heat shock response
D Pincus - HSF1 and molecular chaperones in biology and cancer, 2020 - Springer
The heat shock response (HSR) is characterized by the induction of molecular chaperones
following a sudden increase in temperature. In eukaryotes, the HSR comprises the set of …
following a sudden increase in temperature. In eukaryotes, the HSR comprises the set of …
Reactive oxygen species mediated apoptotic death of colon cancer cells: therapeutic potential of plant derived alkaloids
Colorectal cancer (CRC) is one of the most deaths causing diseases worldwide. Several risk
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …
factors including hormones like insulin and insulin like growth factors (eg, IGF-1) have been …
[HTML][HTML] A novel Huntington's disease assessment platform to support future drug discovery and development
J Wu, L Möhle, T Brüning, I Eiriz, M Rafehi… - International Journal of …, 2022 - mdpi.com
Huntington's disease (HD) is a lethal neurodegenerative disorder without efficient
therapeutic options. The inefficient translation from preclinical and clinical research into …
therapeutic options. The inefficient translation from preclinical and clinical research into …
Potential benefits of phytochemicals from Azadirachta indica against neurological disorders
Azadirachta indica or Neem has been extensively used in the Indian traditional medical
system because of its broad range of medicinal properties. Neem contains many chemically …
system because of its broad range of medicinal properties. Neem contains many chemically …
Genetic studies of heat stress regulation in goat during hot climatic condition
Various direct and indirect environmental constraints have an impact on livestock
performance. The physiological parameters, such as rectal temperature, heart rate, and …
performance. The physiological parameters, such as rectal temperature, heart rate, and …
Bio-active compounds isolated from neem tree and their applications
R Sarah, B Tabassum, N Idrees… - Natural Bio-active …, 2019 - Springer
The extracts of different parts of neem tree (Azadirachta indica) have been well documented
for its pharmacological or medicinal properties and their wide applications by indigenous …
for its pharmacological or medicinal properties and their wide applications by indigenous …
[HTML][HTML] Molecular mechanisms and therapeutics for spinocerebellar ataxia type 2
The effective therapeutic treatment and the disease-modifying therapy for spinocerebellar
ataxia type 2 (SCA2)(a progressive hereditary disease caused by an expansion of …
ataxia type 2 (SCA2)(a progressive hereditary disease caused by an expansion of …
Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence
Background Esculetin is a natural coumarin derivative from various plants with multiple
pharmacological effects. Hence, the present study was undertaken to explore the cardio …
pharmacological effects. Hence, the present study was undertaken to explore the cardio …
Natural bio-active compounds
Secondary metabolites are the unique faction of compounds, produced by plants to protect
itself against the various biotic and abiotic factors (diseases, pests, pathogens, herbivores …
itself against the various biotic and abiotic factors (diseases, pests, pathogens, herbivores …