At the simplest level, neurons are structured to integrate synaptic input and perform
computational transforms on that input, converting it into an action potential (AP) code. This …

This preliminary study sought to assess biomarkers of attention using
electroencephalography (EEG) and eye tracking in two ultra‐rare monogenic populations …

Animal models are instrumental to understanding the mechanisms underlying autism
spectrum disorder, yet translating human behavioral phenotypes remains challenging …

SCN2A encodes the alpha subunit of the voltage-gated sodium channel Nav1. 2, which is
involved in action potential initiation and backpropagation in glutamatergic neurons …

Valproic acid (VPA) is one of the most effective antiepileptic drugs, and exposing animals to
VPA during gestation has been used as a model for autism spectrum disorder (ASD) …

Autism spectrum disorder (ASD) is a complex neuro developmental condition characterized
by significant genetic and phenotypic variability, making diagnosis and treatment …

The signaling complex around voltage-gated sodium (Nav) channels includes accessory
proteins and kinases crucial for regulating neuronal firing. Previous studies showed that one …

Dysfunction in the gene SCN2A, which encodes the voltage-gated sodium channel Nav1. 2,
is strongly associated with neurodevelopmental disorders including autism spectrum …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
complex sensory processing deficits. A key unresolved question is how alterations in neural …

Autism spectrum disorder (ASD) is characterized by a complex etiology, with genetic
determinants significantly influencing its manifestation. Among these, the Scn2a gene …