The procedure of neurogenesis has made numerous achievements in the past decades,
during which various molecular biomarkers have been emerging and have been broadly …

In the central nervous system, oligodendrocytes produce myelin sheaths that enwrap
neuronal axons to provide trophic support and increase conduction velocity. New …

Neurogenesis in adult humans remains a controversial area of research among
neuroscientists. Methodological challenges have hampered investigators from conducting …

Different kinds of experience during early life can play a significant role in the development
of an animal's behavioural phenotype. In natural contexts, this influences behaviours from …

Nanomaterials (NMs) are increasingly used for the therapy, diagnosis, and monitoring of
disease-or drug-induced mechanisms in the human biological system. In view of their small …

Nanoparticle applications are becoming increasingly popular in fields such as photonics,
catalysis, magnetics, biotechnology, manufacturing of cosmetics, pharmaceuticals, and …

Biologists long believed that, once development is completed, no new neurons are
produced in the forebrain. However, as is now firmly established, new neurons can be …

Summary Mutations in presenilin 1 (PSEN1) or presenilin 2 (PSEN2), the catalytic subunit of
γ-secretase, cause familial Alzheimer's disease (fAD). We hypothesized that mutations in …

Adult neurogenesis, defined here as progenitor cell division generating functionally
integrated neurons in the adult brain, occurs within the hippocampus of numerous …

Synapse degeneration occurs early in neurodegenerative diseases and correlates strongly
with cognitive decline in Alzheimer's disease (AD). The molecular mechanisms that trigger …