Marine natural products

JW Blunt, AR Carroll, BR Copp, RA Davis… - Natural product …, 2018 - pubs.rsc.org
Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …

Saponins of North Atlantic Sea Cucumber: Chemistry, health benefits, and future prospectives

OF Fagbohun, JS Joseph, OV Oriyomi… - Marine Drugs, 2023 - mdpi.com
Frondosides are the major saponins (triterpene glycosides) of the North Atlantic sea
cucumber (Cucumaria frondosa). Frondosides possess amphiphilic characteristics due to …

Gambogenic acid induces apoptosis and autophagy through ROS‐mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells

J Wu, D Wang, J Zhou, J Li, R **e, Y Li… - Phytotherapy …, 2023 - Wiley Online Library
Prostate cancer (PCa) is the most common malignant tumor in males, which frequently
develops into castration‐resistant prostate cancer (CRPC) with limited therapies …

Cancer Cell Inhibiting Sea Cucumber (Holothuria leucospilota) Protein as a Novel Anti-Cancer Drug

R Ru, Y Guo, J Mao, Z Yu, W Huang, X Cao, H Hu… - Nutrients, 2022 - mdpi.com
Cancer remains the primary cause of death worldwide. To develop less toxic anti-cancer
drugs to relieve the suffering and improve the survival of cancer patients is the major focus in …

Therapeutic application of diverse marine-derived natural products in cancer therapy

CW Yun, HJ Kim, SH Lee - Anticancer research, 2019 - ar.iiarjournals.org
Natural products (NPs) are useful sources of bioactive compounds and play important roles
in the development and discovery of new drugs for diverse human diseases. Most natural …

In Vivo and Clinical Studies of Sea Cucumber-Derived Bioactives for Human Health and Nutrition From 2012-2021

Q Liang, F Ahmed, M Zhang, N Sperou… - Frontiers in Marine …, 2022 - frontiersin.org
Sea cucumbers are amongst the highest value seafoods available commercially, especially
in the south-east Asian region, primarily due to their nutritional and health benefits as …

Sea cucumber derived triterpenoid glycoside frondoside A: a potential anti-bladder cancer drug

R Ru, G Chen, X Liang, X Cao, L Yuan, M Meng - Nutrients, 2023 - mdpi.com
Bladder cancer is a highly recurrent disease and a common cause of cancer-related deaths
worldwide. Despite recent developments in diagnosis and therapy, the clinical outcome of …

Synthetic and naturally occurring heterocyclic anticancer compounds with multiple biological targets

RK Amewu, PO Sakyi, D Osei-Safo, I Addae-Mensah - Molecules, 2021 - mdpi.com
Cancer is a complex group of diseases initiated by abnormal cell division with the potential
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …

Anticancer and cancer preventive compounds from edible marine organisms

M Correia-da-Silva, E Sousa, MMM Pinto… - Seminars in cancer …, 2017 - Elsevier
A direct impact of food on health, which demonstrates that dietary habit is one of the most
important determinants of chronic diseases such as cancers, has led to an increased interest …