There has clearly been a deluge of international press coverage of the recent outbreak of
Ebolavirus in Africa and is partly related to the “fear factor” that comes across when one is …

Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease
characterized by the sudden onset of fever and malaise accompanied by other non-specific …

Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we
identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical …

Prebiotics are non-digestible oligosaccharides that promote the growth of beneficial gut
microbes, but it is unclear whether they also have direct effects on the intestinal mucosal …

The filovirus VP40 protein directs virion egress, which is regulated either positively or
negatively by select VP40–host interactions. We demonstrate that host BAG3 and HSP70 …

Ebola-and marburgviruses are highly pathogenic filoviruses and causative agents of viral
hemorrhagic fever. Filovirus disease is characterized by a dysregulated immune response …

Understanding the relationship between host and pathogen is key to combatting disease.
SMAD transcription factors, which transmit TGF-β superfamily signalling, mediate an array of …

Transforming growth factor‐β (TGF‐β) signaling pathway is a key network in cell signaling
that controls vital processes such as proliferation, differentiation, apoptosis, epithelial …

The genomic era has increased the research effort to uncover how the genome of an
organism, and specifically the transcriptome, is modulated after interplaying with pathogenic …

Ebola virus (EBOV) is a negative-strand RNA virus that replicates in the cytoplasm and
causes an often-fatal hemorrhagic fever. EBOV, like other viruses, can reportedly encode its …