Guidelines for measuring cardiac physiology in mice

ML Lindsey, Z Kassiri, JAI Virag… - American Journal …, 2018 - journals.physiology.org
Cardiovascular disease is a leading cause of death, and translational research is needed to
understand better mechanisms whereby the left ventricle responds to injury. Mouse models …

[HTML][HTML] Myocardial tagging by cardiovascular magnetic resonance: evolution of techniques–pulse sequences, analysis algorithms, and applications

ESH Ibrahim - Journal of Cardiovascular Magnetic Resonance, 2011 - Elsevier
Cardiovascular magnetic resonance (CMR) tagging has been established as an essential
technique for measuring regional myocardial function. It allows quantification of local …

[SÁCH][B] Understanding mechanisms by which injectable biomaterials affect cardiac function post-myocardial infarction

AA Rane - 2012 - search.proquest.com
Cardiovascular disease affects over 82 million Americans, of which myocardial infarction
(MI) and subsequent heart failure (HF) patients are a major subset. As a result, the …

[HTML][HTML] Evaluation of left ventricular torsion by cardiovascular magnetic resonance

AA Young, BR Cowan - Journal of Cardiovascular magnetic resonance, 2012 - Elsevier
Recently there has been considerable interest in LV torsion and its relationship with
symptomatic and pre-symptomatic disease processes. Torsion gives useful additional …

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model

RC Lyon, V Mezzano, AT Wright… - Human molecular …, 2014 - academic.oup.com
Arrhythmogenic right ventricular cardiomyopathy (ARVC) termed a 'disease of the
desmosome'is an inherited cardiomyopathy that recently underwent reclassification owing to …

Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction

AA Rane, JS Chuang, A Shah, DP Hu, ND Dalton… - PloS one, 2011 - journals.plos.org
Background Several injectable materials have been shown to preserve or improve cardiac
function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction …

Computational approaches to understand cardiac electrophysiology and arrhythmias

BN Roberts, PC Yang, SB Behrens… - American Journal …, 2012 - journals.physiology.org
Cardiac rhythms arise from electrical activity generated by precisely timed opening and
closing of ion channels in individual cardiac myocytes. These impulses spread throughout …

In-silico heart model phantom to validate cardiac strain imaging

T Mukherjee, M Usman, RR Mehdi, E Mendiola… - Computers in Biology …, 2024 - Elsevier
The quantification of cardiac strains as structural indices of cardiac function has a growing
prevalence in clinical diagnosis. However, the highly heterogeneous four-dimensional (4D) …

Transmural gradients of myocardial structure and mechanics: implications for fiber stress and strain in pressure overload

ED Carruth, AD McCulloch, JH Omens - Progress in biophysics and …, 2016 - Elsevier
Although a truly complete understanding of whole heart activation, contraction, and
deformation is well beyond our current reach, a significant amount of effort has been …

Biomedical imaging in experimental models of cardiovascular disease

DE Sosnovik, M Scherrer-Crosbie - Circulation research, 2022 - ahajournals.org
Major advances in biomedical imaging have occurred over the last 2 decades and now
allow many physiological, cellular, and molecular processes to be imaged noninvasively in …