Microfluidic trends in drug screening and drug delivery
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …
cost of bringing a drug from concept to market emphasizes the need for new approaches to …
Advances in microfluidic devices made from thermoplastics used in cell biology and analyses
Silicon and glass were the main fabrication materials of microfluidic devices, however,
plastics are on the rise in the past few years. Thermoplastic materials have recently been …
plastics are on the rise in the past few years. Thermoplastic materials have recently been …
Pyrazolo-benzothiazole hybrids: Synthesis, anticancer properties and evaluation of antiangiogenic activity using in vitro VEGFR-2 kinase and in vivo transgenic …
A series of new pyrazolo-benzothiazole hybrids (7–26) were synthesised and screened for
their cytotoxic activity towards several cancer cell lines [colon (HT-29), prostate (PC-3), lung …
their cytotoxic activity towards several cancer cell lines [colon (HT-29), prostate (PC-3), lung …
Self-contained microfluidic systems: a review
Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and
health conditions using small amounts of biological samples and reagents. Despite these …
health conditions using small amounts of biological samples and reagents. Despite these …
The impact of selected abiotic factors on Artemia hatching process through real-time observation of oxygen changes in a microfluidic platform
Current studies on abiotic impacts on Artemia, a crustacean which is widely used in
aquaculture, and ecotoxicology, often focus on endpoint analysis (eg, hatching rates …
aquaculture, and ecotoxicology, often focus on endpoint analysis (eg, hatching rates …
Fish-on-a-chip: microfluidics for zebrafish research
High-efficiency zebrafish (embryo) handling platforms are crucially needed to facilitate the
deciphering of the increasingly expanding vertebrate–organism model values. However, the …
deciphering of the increasingly expanding vertebrate–organism model values. However, the …
High-throughput screening paradigms in ecotoxicity testing: Emerging prospects and ongoing challenges
The rapidly increasing number of new production chemicals coupled with stringent
implementation of global chemical management programs necessities a paradigm shift …
implementation of global chemical management programs necessities a paradigm shift …
Microfluidics for interrogating live intact tissues
The intricate microarchitecture of tissues–the “tissue microenvironment”–is a strong
determinant of tissue function. Microfluidics offers an invaluable tool to precisely stimulate …
determinant of tissue function. Microfluidics offers an invaluable tool to precisely stimulate …
Microfluidic devices for embryonic and larval zebrafish studies
Zebrafish or Danio rerio is an established model organism for studying the genetic, neuronal
and behavioral bases of diseases and for toxicology and drug screening. The embryonic …
and behavioral bases of diseases and for toxicology and drug screening. The embryonic …
Self-sufficient, low-cost microfluidic pumps utilising reinforced balloons
Here, we introduce a simple method for increasing the inflation pressure of self-sufficient
pressure pumps made of latex balloons. Our method involves reinforcing the latex balloon …
pressure pumps made of latex balloons. Our method involves reinforcing the latex balloon …