Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …

Diabetes mellitus is one of the major public health problems worldwide. Considerable recent
evidence suggests that the cellular reduction-oxidation (redox) imbalance leads to oxidative …

The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

Cancer stem cells (CSC) possess abilities generally associated with embryonic or adult
stem cells, especially self-renewal and differentiation. The CSC model assumes that this …

Stem cells reside in specialized microenvironments known as niches. During Drosophila
development, glial cells provide a niche that sustains the proliferation of neural stem cells …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

The oxidation of bioorganic materials by air and, particularly, the oxidative stress involved in
the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are …

Skin is the largest human organ. Skin continually reconstructs itself to ensure its viability,
integrity, and ability to provide protection for the body. Some areas of skin are continuously …

In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

Abstract Elevated levels of Reactive Oxygen Species (ROS), increased antioxidant ability
and the maintenance of redox homeostasis can cumulatively contribute to tumor progression …