Reproductive diseases are a long‐standing problem and have become more common in the
world. Currently, 15% of the world's population suffers from infertility, and half of them are …

With the continued steep rise of the global human population, and the paucity of safe and
practical contraceptive options available to men, the need for development of effective and …

Azoospermia, which is the absence of spermatozoa in an ejaculate occurring due to defects
in sperm production, or the obstruction of the reproductive tract, affects about 1% of all men …

In the eukaryotic cell cycle, a threshold level of cyclin B accumulation triggers the G2-to-M
transition, and subsequent cyclin B destruction triggers mitotic exit. The anaphase-promoting …

STUDY QUESTION Can any new genetic factors responsible for early embryonic arrest in
infertile patients be identified, together with the mechanism of pathogenic variants …

Spermatogenesis is tightly regulated by ubiquitination and proteasomal degradation,
especially during spermiogenesis, in which histones are replaced by protamine. However …

Abstract TBBPA bis (2-hydroxyethyl) ether (TBBPA-DHEE) pollution in the environment has
raised serious public health concerns due to its potential neuroendocrine-disrupting effects …

Background Hepatocellular carcinoma (HCC) has a high prevalence and poor prognosis
worldwide. Therefore, it is urgent to find effective and timely diagnostic markers. The …

Human Perrault syndrome (PRLTS) is autosomal, recessively inherited, and characterized
by ovarian insufficiency with hearing loss. Among the genetic causes are mutations of matrix …

The meiotic prophase I to metaphase I (PI/MI) transition requires chromosome desynapsis
and metaphase competence acquisition. However, control of these major meiotic events is …