Oxygenation strategies for encapsulated islet and beta cell transplants

KK Papas, H De Leon, TM Suszynski… - Advanced drug delivery …, 2019 - Elsevier
Human allogeneic islet transplantation (ITx) is emerging as a promising treatment option for
qualified patients with type 1 diabetes. However, widespread clinical application of …

Nuclear magnetic resonance spectroscopy and imaging in animal research

JC Chatham, SJ Blackband - IlAR Journal, 2001 - academic.oup.com
Nuclear magnetic resonance (NMR) spectroscopy and imaging can be used to investigate,
noninvasively, a wide range of biological processes in systems as diverse as protein …

[КНИГА][B] Polysaccharides: structural diversity and functional versatility

S Dumitriu - 2004 - taylorfrancis.com
Completely revised and expanded to reflect the latest advancements in the field,
Polysaccharides: Structural Diversity and Functional Versatility, Second Edition outlines …

Differential functional effects of biomaterials on dendritic cell maturation

J Park, JE Babensee - Acta biomaterialia, 2012 - Elsevier
The immunological outcome of dendritic cell (DC) treatment with different biomaterials was
assessed to demonstrate the range of DC phenotypes induced by biomaterials commonly …

Low revascularization of experimentally transplanted human pancreatic islets

PO Carlsson, F Palm, G Mattsson - The Journal of Clinical …, 2002 - academic.oup.com
Pancreatic islets are avascular immediately after transplantation. Although the islets are
rapidly revascularized, it is uncertain whether the revascularization produces an adequate …

Controlling the size of alginate gel beads by use of a high electrostatic potential

TI Klokk, JE Melvik - Journal of microencapsulation, 2002 - Taylor & Francis
The effect of several parameters on the size of alginate beads produced by use of an
electrostatic potential bead generator was examined. Parameters studied included needle …

Enhancing oxygen tension and cellular function in alginate cell encapsulation devices through the use of perfluorocarbons

SF Khattak, K Chin, SR Bhatia… - Biotechnology and …, 2007 - Wiley Online Library
Encapsulation devices are often hindered by the inability to achieve sufficient oxygen levels
for sustaining long‐term cell survival both in vivo and in vitro. We have investigated the use …

Glucose‐stimulated insulin release: parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets

P Buchwald, A Tamayo‐Garcia… - Biotechnology and …, 2018 - Wiley Online Library
To explore the effects immune‐isolating encapsulation has on the insulin secretion of
pancreatic islets and to improve our ability to quantitatively describe the glucose‐stimulated …

A stirred microchamber for oxygen consumption rate measurements with pancreatic islets

KK Papas, A Pisania, H Wu, GC Weir… - Biotechnology and …, 2007 - Wiley Online Library
Improvements in pancreatic islet transplantation for treatment of diabetes are hindered by
the absence of meaningful islet quality assessment methods. Oxygen consumption rate …

Islet assessment for transplantation

KK Papas, TM Suszynski, CK Colton - Current opinion in organ …, 2009 - journals.lww.com
Conclusion More sensitive and reliable islet viability and potency tests have been recently
developed and tested. Those evaluating mitochondrial function are most promising …