An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …

Background Transdiagnostic processes confer risk for multiple types of psychopathology
and explain the co-occurrence of different disorders. For this reason, transdiagnostic …

Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Investigating the developmental sequelae of early life stress has provided researchers the
opportunity to examine adaptive responses to extreme environments. A large body of work …

Highlights•Enhanced threat processing is a mechanism linking child trauma to
psychopathology.•Information processing biases and altered emotional learning are key …

Adolescence is a time in development when significant changes occur in affective
neurobiology. These changes provide a prolonged period of plasticity to prepare the …

This new edition of the bestselling text, Nurturing Natures, provides an indispensable
synthesis of the latest scientific knowledge about children's emotional development …

Early adverse experiences are associated with heighted vulnerability for stress-related
psychopathology across the lifespan. While extensive work has investigated the effects of …

The Research Domain Criteria (RDoC) initiative provides a strategy for classifying
psychopathology based on behavioral dimensions and neurobiological measures …