The principle of vinylogy states that the electronic effects of a functional group in a molecule
are possibly transmitted to a distal position through interposed conjugated multiple bonds …

Fluorine and fluoroalkyl groups wildly exist in organic molecules that are useful in numerous
fields such as biological chemistry, medicinal science, agrochemistry, materials science and …

An electrochemical difluoromethylation triggered lactonization of alkenes was developed for
the first time. This protocol employs readily prepared CF2HSO2Na as the …

An unprecedented carbene-catalyzed radical trifluoromethylation of olefins with aldehydes
in the presence of Togni reagent was developed, thus providing the β-trifluoromethyl-α …

The combination of light activation and N‐heterocyclic carbene (NHC) organocatalysis has
enabled the use of acid fluorides as substrates in a UVA‐light‐mediated photochemical …

N-Heterocyclic carbene (NHC) organocatalysis has emerged as a powerful tool in the field
of modern organic synthesis especially in asymmetric construction of various cyclic …

A novel strategy for the expedient construction of CF3‐embeded tertiary/quarternary carbon
centers was developed by taking advantage of photoredox catalysis. Thanks to a key step of …

Site-selective trifluoromethylation of silyl dienol ethers derived from α, β-unsaturated
aldehydes, ketones, and amides was achieved for the first time in the remote γ position. This …

A strategically novel protocol for ring-opening functionalization of aryl gem-
difluorocyclopropanes (F2CPs), which allows an expedient construction of CF3-containing …

Although breakthroughs in the N-heterocyclic carbene (NHC)-catalyzed inert C–C bond
activation strategy have been achieved, understanding the role of the catalyst as well as the …