Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip

H Liu, Y Wang, K Cui, Y Guo, X Zhang… - Advanced …, 2019 - Wiley Online Library
Significant advances in materials, microscale technology, and stem cell biology have
enabled the construction of 3D tissues and organs, which will ultimately lead to more …

Repeated dose multi-drug testing using a microfluidic chip-based coculture of human liver and kidney proximal tubules equivalents

NI Lin, X Zhou, X Geng, C Drewell, J Hübner, Z Li… - Scientific reports, 2020 - nature.com
A microfluidic multi-organ chip emulates the tissue culture microenvironment, enables
interconnection of organ equivalents and overcomes interspecies differences, making this …

Liver-on-a-chip: Considerations, advances, and beyond

Z Yang, X Liu, EM Cribbin, AM Kim, JJ Li, KT Yong - Biomicrofluidics, 2022 - pubs.aip.org
The liver is the largest internal organ in the human body with largest mass of glandular
tissue. Modeling the liver has been challenging due to its variety of major functions …

Intestine-liver axis on-chip reveals the intestinal protective role on hepatic damage by emulating ethanol first-pass metabolism

V De Gregorio, M Telesco, B Corrado… - … in bioengineering and …, 2020 - frontiersin.org
Intestine-Liver-on-chip systems can be useful to predict oral drug administration and first-
pass metabolism in vitro in order to partly replace the animal model. While organ-on-chip …