Epidemiological evidence suggests the presence of common risk factors for the
development and prognosis of both cardio-and cerebrovascular diseases, including stroke …

Clinical trials of putative disease-modifying therapies in neurodegeneration have obeyed
the century-old principle of convergence, or lum**, whereby any feature of a …

To investigate the causal relationships between cerebrospinal fluid (CSF) metabolites and
various neurodegenerative diseases (NDDs), we conducted a two-sample Mendelian …

Brain imaging genetics investigates the complex relationships between genetic variations
and brain imaging quantitative traits (QTs). However, existing approaches primarily focus on …

Brain imaging genetics provides the foundation for further revealing brain disorder, which
combines genetic variation with brain structure or functions. Recently, sparse canonical …