Liquid biopsy: current technology and clinical applications

M Nikanjam, S Kato, R Kurzrock - Journal of hematology & oncology, 2022 - Springer
Liquid biopsies are increasingly used for cancer molecular profiling that enables a precision
oncology approach. Circulating extracellular nucleic acids (cell-free DNA; cfDNA) …

Cancer biomarkers: emerging trends and clinical implications for personalized treatment

A Passaro, M Al Bakir, EG Hamilton, M Diehn, F André… - Cell, 2024 - cell.com
The integration of cancer biomarkers into oncology has revolutionized cancer treatment,
yielding remarkable advancements in cancer therapeutics and the prognosis of cancer …

[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

J Pascual, G Attard, FC Bidard, G Curigliano… - Annals of …, 2022 - Elsevier
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly develo** a
strong evidence base for use in patients with cancer. The European Society for Medical …

Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Trends in the approval of cancer therapies by the FDA in the twenty-first century

EC Scott, AC Baines, Y Gong, R Moore Jr… - Nature Reviews Drug …, 2023 - nature.com
The cancer treatment landscape has changed dramatically since the turn of the century,
resulting in substantial improvements in outcomes for patients. This Review summarizes …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer

JD Vogel, SI Felder, AR Bhama… - Diseases of the Colon …, 2022 - journals.lww.com
METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …

[HTML][HTML] The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring

SM Batool, A Yekula, P Khanna, T Hsia… - Cell Reports …, 2023 - cell.com
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for
cancer and other diseases. Liquid biopsy allows minimally invasive molecular …

Circulating tumor DNA and liquid biopsy in oncology

DW Cescon, SV Bratman, SM Chan, LL Siu - Nature cancer, 2020 - nature.com
Techniques for analyzing circulating tumor DNA (ctDNA) to detect, characterize and monitor
cancer have matured rapidly. An increasing body of clinical evidence is demonstrating the …

Current and future perspectives of liquid biopsies in genomics-driven oncology

E Heitzer, IS Haque, CES Roberts… - Nature Reviews …, 2019 - nature.com
Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …

Next-generation sequencing in liquid biopsy: cancer screening and early detection

M Chen, H Zhao - Human genomics, 2019 - Springer
In recent years, the rapid development of next-generation sequencing (NGS) technologies
has led to a significant reduction in sequencing cost with improved accuracy. In the area of …