Meiosis: the chromosomal foundation of reproduction

E Bolcun-Filas, MA Handel - Biology of reproduction, 2018 - academic.oup.com
Meiosis is the chromosomal foundation of reproduction, with errors in this important process
leading to aneuploidy and/or infertility. In this review celebrating the 50th anniversary of the …

Evolutionary mysteries in meiosis

T Lenormand, J Engelstädter… - … of the Royal …, 2016 - royalsocietypublishing.org
Meiosis is a key event of sexual life cycles in eukaryotes. Its mechanistic details have been
uncovered in several model organisms, and most of its essential features have received …

[HTML][HTML] BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules

SD Oh, JP Lao, PYH Hwang, AF Taylor, GR Smith… - Cell, 2007 - cell.com
Bloom's helicase (BLM) is thought to prevent crossing-over during DNA double-strand-break
repair (DSBR) by disassembling double-Holliday junctions (dHJs) or by preventing their …

Construction of a 10,000-marker ultradense genetic recombination map of potato: providing a framework for accelerated gene isolation and a genomewide physical …

H Van Os, S Andrzejewski, E Bakker, I Barrena… - Genetics, 2006 - academic.oup.com
An ultradense genetic linkage map with> 10,000 AFLP loci was constructed from a
heterozygous diploid potato population. To our knowledge, this is the densest meiotic …

Meiotic recombination

N Hunter - Molecular genetics of recombination, 2007 - Springer
Crossover recombination is essential for homolog segregation during meiosis. In contrast to
spontaneous mitotic recombination, meiotic recombination is intrinsic being initiated by the …

Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytes

ML Lenzi, J Smith, T Snowden, M Kim, R Fishel… - The American Journal of …, 2005 - cell.com
In humans,∼ 50% of conceptuses are chromosomally aneuploid as a consequence of
errors in meiosis, and most of these aneuploid conceptuses result in spontaneous …

Crossover interference

KJ Hillers - Current Biology, 2004 - cell.com
During prophase of meiosis in most eukaryotes, DNA recombination events between
homologous chromosomes are induced to occur at high frequency, so there are usually …

A rigorous measure of genome-wide genetic shuffling that takes into account crossover positions and Mendel's second law

C Veller, N Kleckner, MA Nowak - Proceedings of the …, 2019 - National Acad Sciences
Comparative studies in evolutionary genetics rely critically on evaluation of the total amount
of genetic shuffling that occurs during gamete production. Such studies have been …

Broad-scale recombination patterns underlying proper disjunction in humans

A Fledel-Alon, DJ Wilson, K Broman, X Wen… - PLoS …, 2009 - journals.plos.org
Although recombination is essential to the successful completion of human meiosis, it
remains unclear how tightly the process is regulated and over what scale. To assess the …

Cryptic sex in the smallest eukaryotic marine green alga

N Grimsley, B Péquin, C Bachy… - Molecular biology …, 2010 - academic.oup.com
Ostreococcus spp. are common worldwide oceanic picoeukaryotic pelagic algae. The
complete genomes of three strains from different ecological niches revealed them to …